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Evaluate effect of biological therapy on activity of RA compared to usual DMARDs
Comparison between RA activity in both groups who recieved biological and DMARDS therapy
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| RA patients recieved biological therapy | RA patients recieved different biological therapy | ||
| RA patients recieved different DMARDS | RA patients recieved different DMARDS |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Biological Drug | Drug | Different biological drugs |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in activity of rheumatoid arthritis | By DAS 28; it include 28 tender and swollen joints, laboratory test (ESR) and visual analogue score, if it higher than 5.1 it mean high disease activity and if lower than 3.2 it mean low activity and consider remission if lower than 2.6 | After 3 months of treatment |
| Measure | Description | Time Frame |
|---|---|---|
| Activity of RA | MHAQ.scores include questionnaire from eight activities of daily living and range from 0 to 3 and lower scores mean better function state and high scores mean worse function state | 3 months after treatment |
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Inclusion Criteria:
Exclusion Criteria:
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RA patients
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| N M Mansour | Contact | 01004517558 | nesmamansour971@yahoo.com |
| Name | Affiliation | Role |
|---|---|---|
| N M AHM, Specialist | Sohag faculty of medicine | Principal Investigator |
| M M AHM | Sohag faculty of medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sohag faculty of medicine | Sohag | Sohag Governorate | Egypt |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Jan 6, 2026 | |
| Reset | Jan 21, 2026 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Jan 6, 2026 | Jan 21, 2026 |
| ID | Term |
|---|---|
| D001172 | Arthritis, Rheumatoid |
| ID | Term |
|---|---|
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D012216 | Rheumatic Diseases |
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| ID | Term |
|---|---|
| D001688 | Biological Products |
| D018501 | Antirheumatic Agents |
| C031927 | hydroquinone |
| D008727 | Methotrexate |
| ID | Term |
|---|---|
| D045424 | Complex Mixtures |
| D045506 | Therapeutic Uses |
| D020228 | Pharmacologic Actions |
| D020164 | Chemical Actions and Uses |
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| D003240 |
| Connective Tissue Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
| D000630 |
| Aminopterin |
| D011622 | Pterins |
| D011621 | Pteridines |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D006571 | Heterocyclic Compounds |