Revascularisation of Autotransplanted Teeth

Revascularisation of Autotransplanted Teeth - Retrospective Analysis of a Novel Technique

Retrospective Analysis of a Study cohort that experienced autotransplantation of mature teeth with simultaneous root end resection

Note: The study was registered on Clinicaltrials.gov after termination of study.

Inclusion Criteria:

• Male and female consenting and judicious young people and adults
• Written consent of the participant and, if applicable, of the legal guardian after education
• Planned tooth transplantation with advanced or completed root growth

Exclusion Criteria:

• Contraindications for magnetic resonance imaging (MRI): (pronounced metal restorations, running orthodontics with metal, fixed appliance in the target jaw)
• Current or past antiresorptive therapy with bisphosphonates
• Further anamnestic general or local risk situation, among others: Anti-angiogenic therapy, History of local radiation therapy, severe coagulation disorder, unadjusted diabetes mellitus, malignant diseases
• Acute gingivitis or advanced periodontitis
• Participation in an ongoing drug trial (various drugs may distort the result, such as bisphosphonates, cortisone, chemotherapeutics, angiogenesis inhibitors)
• heavy smokers (> 10 per day)
• Acute or chronic infections (osteomyelitis) at the surgical site
• metabolic diseases (diabetes, hyperparathyroidism, osteomalacia)
• Severe kidney dysfunction, severe liver disease
• Patients with high-dose corticosteroid therapy
• prolonged corticosteroid or radiotherapy in the oral cavity
• autoimmune diseases
• Pregnant or breastfeeding women