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achievement of optimal postnatal growth by adequate enteral nutrition in critically ill preterm infants is a challenge of NICU. signs like abdominal distension, reflux, vomiting, nec is a factors of discontinuing fedding in preterm. this factors plays a role in decisions about which method of gavage feeding is adopted. we compare two different feeding method to achive less fedding tolerence.
<1750 gr, <33 gw infants will enroll study. exckusion criteria: major congenital anomalies major gis anomalies
The study infants are enrolled within 24 hours of birth and sequently randomized to either intermitten feeding (IF) and bolus feeding (BF). Intermittent feeding is defined as delivering enteral nutrition and generally giving 60 min and 2 hours no feeding. this circle repeats 8 times in 24 hours. Bolus feeding is the amount of nutrition put into the syringe was kept 10 cm above the baby and the fluidity was obtained by gravity through the orogastric tube. The data of the patients such as feeding intolerance (gastric residual volume more than %50 of the previous feeding volume, gastric regurgitation, abdominal distension and/or emesis ), whether there is a week-by-week feeding intolerance were noted, NEC, time to reached birth weight, time to achieved full enteral feeding, every 5 minutes during feeding, saturation, respiratory rate and heart rates will record.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| bolus feeding group | Other | In bolus feednig group preterm fed by via gravity drip over a short period, usually 15-20 min. it administrated 8-12 times daily |
|
| intermittant feeding group | Other | Intermittant feeding is delivered over a 30-60 min by infusion pump. it administrated 8-12 times daily |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| bolus/intermittant feeding | Other | sequential randomization |
|
| Measure | Description | Time Frame |
|---|---|---|
| rate of feeding intolerence | The effect of two different gavage tube feeding methods on feeding intolerance | 1 month |
| Measure | Description | Time Frame |
|---|---|---|
| time to reach full enteral feeding | The effect of two different gavage tube feeding methods on time to reach full enteral feeding | 1 month |
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Inclusion Criteria:
Exclusion Criteria:
major congenital anomalies gis anomalies septic shock exitus in 3 days of life
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| Name | Affiliation | Role |
|---|---|---|
| Funda Yavanoğlu Atay, md | Zekai Tahir Burak Women's Health Research and Education Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ümraniye Teaching Hospital | Istanbul | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34355390 | Background | Richards R, Foster JP, Psaila K. Continuous versus bolus intermittent intragastric tube feeding for preterm and low birth weight infants with gastro-oesophageal reflux disease. Cochrane Database Syst Rev. 2021 Aug 6;8(8):CD009719. doi: 10.1002/14651858.CD009719.pub3. |
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| ID | Term |
|---|---|
| D047928 | Premature Birth |
| ID | Term |
|---|---|
| D007752 | Obstetric Labor, Premature |
| D007744 | Obstetric Labor Complications |
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
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| D000091642 | Urogenital Diseases |