Administrative issues.

This is a single centre, single arm feasibility study assessing the feasibility of using computer vision methods to recreate the 3D bladder shape and to then map the cystoscopy images onto this bladder shape. If feasible, this 3D reconstructed shape would be spatially registered to radiological images (CT, MR) that are then used during radiation treatment planning. This analysis would not be used for making any clinical treatment decisions on the patient.

Inclusion Criteria:

• 18 years of age or older.
• Clinical suspicion or histologic diagnosis of bladder tumour suitable for endoscopic evaluation.
• Intention to treat using external beam radiation therapy as part of standard of care.
• Ability to provide written informed consent to participate in the study.

Exclusion Criteria:

• Prior complete or partial radiation therapy to bladder.
• Contraindications to radiation therapy as determined by the treating physician.
• Concurrent illness or condition that precludes subject from undergoing endoscopy or CT scanning.

Patients with clinical suspicion or histologic diagnosis of bladder tumour suitable for endoscopic evaluation and intent to treat using external beam radiation therapy.