A prospective, randomized, controlled study was conducted to identify patients with end-stage renal disease who required open peritoneal dialysis catheterization, preoperative enema or no enema was used to evaluate the efficacy and safety of reducing catheter dysfunction.

A prospective, randomized, controlled study was conducted to identify patients with end-stage renal disease who required open peritoneal dialysis catheterization, preoperative enema or no enema was used to evaluate the efficacy and safety of reducing catheter dysfunction. All the patients were divided into two groups: preoperative enema group and no intervention group. The peritoneal dialysis malfuction were observed.

Inclusion Criteria:

• Age ≥18;
• Maintenance peritoneal dialysis treatment is required for end-stage Renal Disease;
• First-time open surgeon peritoneal dialysis catheterization patient;
• Only straight double-cuff Tenckhoff dialysis catheters were used.
• Willing to participate in this study and sign informed consent form.

Exclusion Criteria:

• peritoneal dialysis contraindication;
• Enema contraindication;
• Patients refuse enema;
• Expected survival time < 3 months;
• Catharsis such as Senna Leaf and lactulose used before operation or colonic dialysis and enema used 3 days before operation.