The purpose of this trial is to evaluate the feasibility of a home based exercise program for individuals with breast or prostate cancer patients undergoing active treatment.

This feasibility trial aims to assess a home-based exercise program, including a 3-month intervention of structured physical activity and health education for individuals with breast or prostate cancer. The main objective of this trial is to assess the adherence of cancer patients to a program of structured exercise, mixed with a health education approach, implemented and accompanied in a remote approach.

The data collection will include variables related to: (a) recruitment and retentions rates; (b) attendance to exercise sessions; (c) fatigue and quality of life levels; (d) functional capacity levels; (e) adverse events related or not to the study; (f) patient selected outcomes.

Inclusion Criteria:

• eighteen years old minimum;
• be living in Porto Alegre or metropolitan region;
• breast cancer stage 0 - III OR
• localized prostate cancer;
• undergoing hormonal treatment / manipulation in isolation or combined with other therapies three months prior to the entrance in the study;
• hormonal therapy / manipulation planned to be active throughout the study duration;
• not engaged in any exercise training for more than once a week for the past 6 months;
• in case of previous surgical procedure, the patient must have medical clearance at the moment of the contact to begin the study or be cleared to do so in the near future (up to two weeks).

Exclusion Criteria:

• metastatic phase / progression of the disease or active regional location prior to beginning of the study;
• inability to understand the terms and conditions of study due to language, hearing, cognitive or severe psychiatric issues;
• another family member, who lives at the same residence, participating in the study;
• planning to move or major absence (more than two weeks) during the study;
• history of cardiovascular disease (except controlled hypertension) or severe cardiopulmonary disease, as well as history of heart attack, revascularization procedures, profound venous thrombosis, encephalic vascular accident (brain stroke) or pulmonary embolism in the past twelve months;
• chronic pulmonary disease that requires oxygen or corticosteroid therapy;
• kidney disease with or that is going to begin the use of dialysis or waiting for a kidney transplant;
• severe nausea, anorexia or any other condition which does not allow to perform physical exercise;
• medical contraindication to exercise training.

The trial is designed for female breast cancer patients and male prostate cancer patients.

Files will be as de-identified as possible before public data sharing. After data protection and data handling routines, de-identified data will be readily available to all project contributors. We consider research data gathered from data collection from research participants pertains primarily to these individuals. Therefore, all individual data will be available to their owners throughout the project. Structured data that will result from this research project will pertain to the PI (Daniel Umpierre), who will be responsible for data integrity, and to the institution (Hospital de Clinicas de Porto Alegre).

The specific structure for data sharing as well as plataforms are still to be defined. As soon, we define the remaining details of our data sharing strategy the IPD plan will be updated.

Due to space and management constraints, we are planning:

1. To retain and store project documentation (informed consents, IRB communication, subjects' communication) for at least 10 years after the study completion (anticipated time: up to 2033).
2. To retain and share project resources (instruments, intervention materials) as long as public repositories (e.g., Zenodo, OSF, figshare) provide sharing services at no cost.
3. To retain and share datasets as long as public repositories (e.g., Zenodo, OSF, figshare) provide sharing services at no cost.

All the files will be password-protected and only investigators or data managers designated to use the files will be given access. Different passwords will be used for different users, which allows auditing to be made more easily. Although we do not plan to request justification to release the datasets, we do plan to share the data in a controlled approach. Therefore, once the datasets are made available at the Zenodo.org platform, only registered users will be able to download files. This procedure allows us to keep a record of data requests.