Fever of Unknown Orgin Registry in Internal Medicine Unit and Infectious Disease Units

Fever of Unknown Orgin Registry in Internal Medicine Unit and Infectious Disease Units

This registry has the aim to collect epidemiological and clinical data of classical FUO cases in Italian Internal medicine Dept. and in Italian Infection diseases Dept.

In particular this registry intends to record clinical data observed, diagnostic methods used and the clinical evolution of classical FUO cases

Inclusion Criteria:

• • fever (temperature > 38.3° C) found in several occasions of a duration exceeding 3, unable to make a diagnosis after a period of 3 days of hospitalization or after 3 out-patients visits in Internal Medicine Dept. or Infection Diseases Dept.

  • signed informed consent

Exclusion Criteria:

• • immunocompromised patients

  • patients in treatment with steroidi (prednisone > 0,5 mg/Kg/die per > 4 weeks), anti-TNF, ciclofosfamide, tacrolimus, everolimus, sirolimus, azatioprina, ciclosporina, micofenolato, metotrexate
  • neutropenic patients with less than 500 neutrofili/µL
  • HIV positive patients
  • nocosomial fever.