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This study is a retrospective study with a propensity score-matched analysis in order to balance differences between patients with D1 and D2 lymphadenectomy for gastric cancer.The main aim is to analyse differences in the postoperative and oncological outcomes of patients with gastric cancer (GC) who underwent D1 and D2 gastrectomy.
In this propensity score-matched analysis of 128 patients, D2 lymphadenectomy improved long-term outcomes compared with D1 in patients with curative intent surgery for gastric cancer except for the group of patients older than 75 years and with early tumors.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| D1 lymph node dissection (LND) | Patients with gastric cancer that underwent curative surgery with gastrectomy and D1 lymph node dissection | ||
| D2 lymph node dissection (LND) | Patients with gastric cancer that underwent curative surgery with gastrectomy and D2 lymph node dissection |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Lymphadenectomy type | Procedure | D1 vs D2 lymph node dissection |
|
| Measure | Description | Time Frame |
|---|---|---|
| Disease-free survival | Disease-free survival (DFS) was defined as the time from gastric surgery to the date of recurrence (locoregional, peritoneal recurrence and/or distant metastases). | percentage of patients without disease recurrence alive at 3 and 5 years after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Overall survival | Overall survival (OS) was defined as the time from the date of surgery to the date of death from any cause | percentage of patients alive at 3 and 5 years after surgery |
| Postoperative morbidity |
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Inclusion Criteria:
Exclusion Criteria:
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A retrospective study was carried out in all consecutive patients diagnosed with GC who underwent curative-intent surgery between April 1999 and October 2019
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| ID | Term |
|---|---|
| D013274 | Stomach Neoplasms |
| ID | Term |
|---|---|
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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Surgical complications were defined as any deviation from the normal postoperative course within 90 days after surgery, both during the hospital stay or after discharge.
| from the surgery up to 90 days after the surgery |
| Postoperative mortality | Mortality through post-operative follow-up | from the surgery up to 90 days after the surgery |
| D004066 |
| Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D013272 | Stomach Diseases |