Effects of Topical Gentamicin on the Prevention of Peritoneal Dialysis Related Infection

Effects of Topical Gentamicin on the Prevention of Peritoneal Dialysis Related Infection Caused by Pseudomonas Aeruginosa

Peritoneal dialysis-related infection is a complication that leads to peritoneal dialysis catheter removal or patient death. The present study aimed to investigate peritoneal dialysis-related infection, causative pathogens resulting in topical 2% mupirocin ointments period compare with 0.1% gentamicin cream period. Rate of catheter removal, time to first peritoneal dialysis-related infection after apply gentamicin cream.

Inclusion Criteria:

• Age greater than or equal to 20 years
• End stage renal disease patients on peritoneal dialysis follow up at Phramongkutklao hospital's peritoneal dialysis clinic between January 1, 2021 to March 31, 2023
• Start peritoneal dialysis or follow up at Phramongkutklao hospital's peritoneal dialysis clinic at least 90 days before recruited
• Use topical mupirocin ointment for prevention of peritoneal dialysis-related infection between January 1, 2021 to December 31, 2021
• Can be used LINE application throughout the study

Exclusion Criteria:

• Allergy to gentamicin or components
• Previous systemic antibiotics use within 90 days before recruited
• Previous peritoneal dialysis-related infection within 28 days before recruited
• Immunosuppressants used
• Prospective follow up less than 2 months
• Don't sign informed consent