Regulatory

The purpose of the study is to do a direct comparison of the CONVIVO system (camera imaging device) with our normal Stanford pathology process. CONVIVO system is being tested to see if the device creates the images very quickly by touching a special camera to the surgical wound.

Primary Objective:

The primary objective of this study is to determine the feasibility of using the CONVIVO imaging system to identify tumor type.

Secondary Objective: The secondary objectives are to determine the average time needed for tissue visualization with the CONVIVO system as compared to standard cryosectioning, and to describe the ability of the CONVIVO imaging

-To describe the ability of the CONVIVO imaging system to generate readable images.

Inclusion Criteria:

• The subject demonstrates the ability to understand and the willingness to sign a written informed consent document.
• The subject is suspected to be suffering from following brain tumor: low-grade glioma, high grade-glioma, metastases, or meningioma.
• The subject has been deemed eligible for surgical resection by a practicing Stanford physician.
• Macroscopic tumor visualization using IV infusion of 500mg sodium fluorescein is planned as part of the subject's standard of care treatment.
• The subject is older than 18 years.
• The subject is receiving their surgery at Stanford Hospital.

Exclusion Criteria:

* Patients with any kind of contraindication to the use of fluorescein