Haloperidol and Dexamethasone Towards Postoperative Nausea and Pain in Adult After Laparoscopy

Haloperidol Compared to Dexamethasone in Lowering Postoperative Nausea and Vomiting and Pain in Adult After Laparoscopy

This study aim to find out the effectiveness of 1 mg intravenous haloperidol compared to 5 mg intravenous dexamethasone to prevent the occurrence of nausea and vomiting also as pain control in adult patients after laparoscopic surgery.

Eighty subjects (n=40 for each group) scheduled for laparoscopic-assisted surgery were enrolled in a randomized double-blind clinical trial. One milligram intravenous haloperidol was given one hour before the end of surgery, while 5 mg intravenous dexamethasone was given right after induction. The occurrence of Postoperative Nausea and Vomiting (PONV) and visual analog scale (VAS) pain score were recorded.

Inclusion Criteria:

• underwent laparoscopic surgery (gynecology, digestive, or urology surgery)
• American Society of Anesthesiologist (ASA) physical status 1-3

Exclusion Criteria:

• psychological or neurological disorders (routine haloperidol consumption)
• history of allergic reaction to dexamethasone or haloperidol
• diabetes mellitus
• did not give the consent