Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Taking into account the high number of COVID-19 patients managed in Italian Internal Medicine, Fadoi Foundation (Italian Scientific Society of Internal Medicine) promotes a national retrospective observational study in patients treated with Remdesivir, analyzing the characteristics of patients and their clinical outcome during hospitalization, and thus providing real-life information potentially useful to integrate the evidence produced by studies conducted under experimental conditions and available in the literature.
This is a multicenter observational, retrospective study, which involves the participation of 35 Nationally Representative Internal Medicine Units, for each center data on all patients suffering from SARS-CoV-2 and treated with Remdesivir are expected to be recorded. Each center will have the task of collecting the data of patients hospitalized consecutively proceeding backwards until March 2020.
The study is a no-profit scientific project, promoted by The FADOI Foundation, the Scientific Society of Internal Medicine.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| COVID-19 patients treated with Remdesivir | Patients suffering from SARS-CoV-2 and treated with Remdesivir admitted to Internal Medicine Unit |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| no experimental intervention | Other | There will not be any experimental intervention. The study will be conducted according with normal clinical practice |
|
| Measure | Description | Time Frame |
|---|---|---|
| characteristics of COVID-19 patients | describe, under conditions of normal clinical practice ("real-life") the different clinical characteristics of patients suffering from SARS-CoV-2, hospitalized in Internal Medicine and treated with Remdesivir | 2 months |
| methods of treatment with Remdesivir and the main outcomes | evaluate the methods of treatment with Remdesivir (initiation of therapy with respect to the onset of symptoms) and the main outcomes (duration of hospitalization, possible clinical worsening, side effects, transfer to Intensive Care, mortality). | 2 months |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
The study includes all consecutive patients aged ≥ 18 years diagnosed with radiologically documented SARS-CoV-2 pneumonia, treated with Remdesivir (according to the criteria defined by AIFA*) and admitted to Internal Medicine from March 2020 to August 2021.
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Andrea Fontanella, MD | FADOI FOUNDATION | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ospedale "Mons. Giovanni Galliano" | Acqui Terme | (AL) | Italy | |||
| Ente Ecclesiastico "F. Miulli" |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Acquaviva delle Fonti |
| (BA) |
| Italy |
| Ospedale di Andria | Andria | (BT) | Italy |
| P.O. di Garbagnate | Garbagnate Milanese | (MI) | Italy |
| Ospedale di Melegnano | Melegnano | (MI) | Italy |
| Ospedale Broni-Stradella | Stradella | (PV) | Italy |
| P.O. di Polistena | Polistena | (RC) | Italy |
| AO "Giuseppe Foscati" | Avellino | Italy |
| Ospedale "S. Paolo" | Bari | Italy |
| Ospedale di Bentivoglio | Bologna | Italy |
| Ospedale Maggiore di Bologna Medicina D | Bologna | Italy |
| P.O. "SS. Trinità " | Cagliari | Italy |
| Ospedale M. Bufalini di Cesena | Cesena | Italy |
| Ospedale di Alba e Bra | Cuneo | Italy |
| Ospedale di Faenza | Faenza | Italy |
| AOU Careggi | Florence | Italy |
| Ospedale "Careggi" | Florence | Italy |
| P.O di Frattamaggiore | Frattamaggiore | Italy |
| Ospedale Galliera | Genova | Italy |
| Ospedale del Mare | Naples | Italy |
| Azienda Ospedaliero Universitaria di Novara | Novara | Italy |
| A.O.U. di Perugia | Perugia | Italy |
| Ospedale di Rimini - Medicina 1 COVID | Rimini | Italy |
| Ospedale di Rimini -Sub intensiva COVID | Rimini | Italy |
| Ospedale "Vannini" | Roma | Italy |
| Ospedale Fatebenefratelli Isola Tiberina | Roma | Italy |
| PO SS Annunziata AOU Sassari | Sassari | Italy |
| Ospedale "San Paolo" di Savona | Savona | Italy |
| Ospedale "Mauriziano" | Torino | Italy |
| Ospedale "Circolo-Macchi" | Varese | Italy |