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This research is a case-control study aiming to characterize motor peculiarities (objective quantitative and qualitative measures) and its psycho-physiological correlates of children with ASD.
The main objective is to measure jointly and in an automated and standardized manner the performance and motor patterns within the framework of tasks measuring the performance and patterns of general motor skills (postures, walking, coordination overall), fine motor skills (graphics, pointing task) and oculomotricity (visual orientation and control).
The secondary objective is to investigate the relationships between motor difficulties and cognitive and social disorders found in children with ASD.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Epidemiology | Other | Recording of participant's performance during eye, fine motor and gross motor tests Passing self and hetero questionnaires. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Testing of general motor skills, fine motor skills and occulomotricity | Behavioral | Recording of participant's performance during eye, fine motor and gross motor tests; Children's gross motor skills will be assessed through a biomechanical analysis. Eye movements will be recorded using the eye-tracking system (Tobii Pro TX300). The technique used is the corneal reflection technique. |
| Measure | Description | Time Frame |
|---|---|---|
| Measurement performance of fine motor skills (graphics, pointing task) | Jointly and in an automated and standardized manner, measure performance in the context of tasks measuring the performance and patterns of general motor skills (postures, walking, overall coordination), fine motor skills (graphics, pointing task) and oculomotricity (visual orientation and control). | At 3 month |
| Measurement performance of general motor skills with biomechanical analysis | Jointly and in an automated and standardized manner, measure motor patterns in the context of tasks measuring the performance and patterns of general motor skills (postures, walking, overall coordination), fine motor skills (graphics, pointing task) and oculomotricity (visual orientation and control). | At 3 month |
| Measurement of oculomotricity with eye-tracking system (visual orientation and control) | Jointly and in an automated and standardized manner, motor patterns in the context of tasks measuring the performance and patterns of general motor skills (postures, walking, overall coordination), fine motor skills (graphics, pointing task) and oculomotricity (visual orientation and control). | At 3 month |
| Measure | Description | Time Frame |
|---|---|---|
| Motor performance : success, error rate (%) | At visit 1 and visit 2, an average of 3 months | |
| Motor performance : task duration (ms), reaction time (ms) and latency (ms) | At visit 1 and visit 2, an average of 3 months |
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Inclusion Criteria :
All participants :
Participants with ASD should also verify the following inclusion criteria:
Exclusion Criteria :
All participants :
Participants without ASD :
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Anouck AMESTOY, MD | Contact | 05 56 56 67 19 | aamestoy@ch-perrens.fr | |
| Helen SAVARIEAU | Contact | 05 56 56 35 56 | hsavarieau@ch-perrens.fr |
| Name | Affiliation | Role |
|---|---|---|
| Anouck AMESTOY, MD | Physician | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre Hospitalier Charles Perrens | Recruiting | Bordeaux | 33076 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30618953 | Result | Biffi E, Costantini C, Ceccarelli SB, Cesareo A, Marzocchi GM, Nobile M, Molteni M, Crippa A. Gait Pattern and Motor Performance During Discrete Gait Perturbation in Children With Autism Spectrum Disorders. Front Psychol. 2018 Dec 11;9:2530. doi: 10.3389/fpsyg.2018.02530. eCollection 2018. | |
| 28748333 | Result | Cazalets JR, Bestaven E, Doat E, Baudier MP, Gallot C, Amestoy A, Bouvard M, Guillaud E, Guillain I, Grech E, Van-Gils J, Fergelot P, Fraisse S, Taupiac E, Arveiler B, Lacombe D. Evaluation of Motor Skills in Children with Rubinstein-Taybi Syndrome. J Autism Dev Disord. 2017 Nov;47(11):3321-3332. doi: 10.1007/s10803-017-3259-1. |
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|
| Questionnaires | Behavioral | Passing self and hetero questionnaires. |
|
| IQ as assessed using WISC IV | At visit 1 and visit 2, an average of 3 months |
| Score of socio-communicative skills as assessed using Social Responsiveness Scale | Social Responsiveness Scale : Min = 30, Max=90 Higher scores mean a worse outcome | At visit 1 and visit 2, an average of 3 months |
| ADHD as assessed using Conners-3 | At visit 1 and visit 2, an average of 3 months |
| Developmental Coordination Disorder as assessed using Developmental Coordination Disorder Questionnaire | Developmental Coordination Disorder Questionnaire : Min = 15, Max = 75 Higher scores mean a better outcome | At visit 1 and visit 2, an average of 3 months |
| ASD Clinical Assessment as assessed using Childhood Autism Rating Scale | Childhood Autism Rating Scale : Min = 0, Max = 100 Higher scores mean a worse outcome | At visit 1 and visit 2, an average of 3 months |
| Centre Hospitalier La Rochelle Re Aunis | Recruiting | La Rochelle | 17019 | France |
|
| CHU de LIMOGES | Recruiting | Limoges | 87042 | France |
|
| Centre Hospitalier Henri Laborit | Recruiting | Poitiers | 86021 | France |
|
| 26594140 | Result | D'Mello AM, Stoodley CJ. Cerebro-cerebellar circuits in autism spectrum disorder. Front Neurosci. 2015 Nov 5;9:408. doi: 10.3389/fnins.2015.00408. eCollection 2015. |
| 32408186 | Result | Eggleston JD, Harry JR, Cereceres PA, Olivas AN, Chavez EA, Boyle JB, Dufek JS. Lesser magnitudes of lower extremity variability during terminal swing characterizes walking patterns in children with autism. Clin Biomech (Bristol). 2020 Jun;76:105031. doi: 10.1016/j.clinbiomech.2020.105031. Epub 2020 May 7. |
| 24349379 | Result | Hak L, Houdijk H, Beek PJ, van Dieen JH. Steps to take to enhance gait stability: the effect of stride frequency, stride length, and walking speed on local dynamic stability and margins of stability. PLoS One. 2013 Dec 13;8(12):e82842. doi: 10.1371/journal.pone.0082842. eCollection 2013. |
| ID | Term |
|---|---|
| D000067877 | Autism Spectrum Disorder |
| D060825 | Cognitive Dysfunction |
| D001519 | Behavior |
| ID | Term |
|---|---|
| D002659 | Child Development Disorders, Pervasive |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |
| D003072 | Cognition Disorders |
| D019965 | Neurocognitive Disorders |
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| ID | Term |
|---|---|
| D011795 | Surveys and Questionnaires |
| ID | Term |
|---|---|
| D003625 | Data Collection |
| D004812 | Epidemiologic Methods |
| D008919 | Investigative Techniques |
| D017531 | Health Care Evaluation Mechanisms |
| D011787 | Quality of Health Care |
| D017530 | Health Care Quality, Access, and Evaluation |
| D011634 | Public Health |
| D004778 | Environment and Public Health |
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