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Through our study, we aim to understand the most important factors for patients when they decide on the type of treatment they receive for MIBC. Our study consists of a discrete choice experiment (DCE): a type of questionnaire used to elicit preferences in the absence of data. DCEs are frequently used in oncological research to elicit preferences from participants without directly asking them to state their preferred options. Participants undertaking our DCE questionnaire will presented with a series of alternative hypothetical scenarios containing several variables or "attributes" (5), each of which may have a number of variations or "levels".
The study will be conducted using validated and established protocols for undertaking DCEs. A literature review was undertaken to assess what the most important considerations where for patients when making decisions about the treatment they receive for MIBC. Using this literature search as a starting point, discussion groups with relevant healthcare professionals and service users were undertaken to decide on the final attribute and levels for the questions. Five attributes were selected through an iterative process - Body image, Life expectancy, Side-effects from treatment, Living as bladder cancer survivor, and Sexual wellbeing
The study is divided into three stages:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pilot study (n = 10) | 10 participants will be recruited to complete the questionnaire (version 1). A research assistant will be present to help support them /answer any questions around the format. Readability and comprehension will be noted. Any changes (if needed) can be implemented to its format before the main data collection. |
| |
| Discrete Choice Experiment Questionnaire (n = 50) | Discrete Choice Experiment (DCE) Patients |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Discrete Choice Experiment (DCE) Patients DCE Questionnaire | Other | Discrete Choice Experiment (DCE) Patients |
|
| Measure | Description | Time Frame |
|---|---|---|
| Willingness to accept treatment attributes, and trade-offs between these, using a study-specific Discrete Choice Experiment (DCE) Questionnaire | Through study completion, an average of 1 year (Discrete Choice Experiment (DCE) Questionnaire). Trade-off from Marginal Rate of Substitution calculate as percentage points (0 to 100). ] |
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Inclusion Criteria:
Exclusion Criteria:
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Men or women with diagnosed MIBC who are currently undergoing treatment or have previously completed treatment for MIBC
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Simon Hughes, MD | Contact | +44 20 7188 3761 | Simon.1.hughes@kcl.ac.uk | |
| Liam Mannion | Contact | +44 20 7140 5685 | Liam.mannion@kcl.ac.uk |
| Name | Affiliation | Role |
|---|---|---|
| Simon Hughes | KCL/GSTTH | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Guy's and St Thomas' NHS Foundation Trust | Recruiting | London | United Kingdom |
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| Semi-Structured Interview Patients Interview | Other | First version of questionnaire (readability/comprehension check) |
|
|
| ID | Term |
|---|---|
| D017060 | Patient Satisfaction |
| D057240 | Patient Preference |
| ID | Term |
|---|---|
| D000074822 | Treatment Adherence and Compliance |
| D015438 | Health Behavior |
| D001519 | Behavior |
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| ID | Term |
|---|---|
| C022673 | delta 24-sterol reductase |
| D010865 | Pilot Projects |
| ID | Term |
|---|---|
| D016020 | Epidemiologic Study Characteristics |
| D004812 | Epidemiologic Methods |
| D008919 | Investigative Techniques |
| D005069 | Evaluation Studies as Topic |
| D017531 | Health Care Evaluation Mechanisms |
| D011787 | Quality of Health Care |
| D017530 | Health Care Quality, Access, and Evaluation |
| D011634 | Public Health |
| D004778 | Environment and Public Health |
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