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COVID-19 infection are characterized by fever and signs of acute respiratory infection. A worsening of respiratory symptoms that can lead to respiratory failure. The decompensation can then be brutal and require rapid recourse to respiratory assistance. The contribution of clinical examination (auscultation and monitoring of oxygen saturation in particular) remains unsatisfactory in predicting an unfavorable course. The interest of pulmonary ultrasound is known in the management of pulmonary infections. However, estimating the severity of lung damage at an early stage could be of great help in monitoring and caring for patients. Ultrasound could meet this need in general practice, the chest scanner is often unavailable in these situations.
Ultrasound signs are associated with severe forms. The contribution of pulmonary ultrasound seems particularly interesting in the context of the reassessment of patients during the worsening phase of symptoms (D5-D10).
Estimate the prevalence of ultrasound signs in patients with an acute respiratory infection suspected or confirmed to be COVID-19, at the time of the worsening phase (between D5 and D10 of the onset of symptoms).
The prevalence of ultrasound lung lesions under COVID-19 may be essential to consider the development of the ultrasound tool in primary care. Indeed, if the contribution of ultrasound is now recognized in intensive care or emergency, its place in general medicine still raises questions.
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| Measure | Description | Time Frame |
|---|---|---|
| Ultrasound Signs | Frequency of the presence of at least one ultrasound sign in the subjects included | Between day 5 and day 10 of infection |
| Measure | Description | Time Frame |
|---|---|---|
| Clinical Signs | Clinical signs positives in the cas of presence one of these elements: Hypoxia, Tachypnée, Pathological pulmonary auscultation. | Day 5 and Day 10 |
| Ultrasound signs | Ultrasound signs positives in the case of presence one of these elements: Disappearance of lines A, Appearance of three lines B, Appearance of pulmonary condensation. |
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Inclusion Criteria:
Patients over 18 years of age with :
a clinical symptomatology suggesting an acute respiratory infection linked to COVID-19 defined by the following two categories of symptoms:
an acute respiratory infection confirmed to COVID-19 by the result of RT-PCR screening tests.
And presenting, at the time of inclusion between the 5th and 10th day of infection, one of the respiratory signs of severity felt:
Exclusion Criteria:
The presence of a severe form during the initial consultation. A severe form is defined by the presence of the following signs:
The presence of acute respiratory signs clearly having a cause other than a COVID-19 infection.
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Adults with acute respiratory infection linked to COVID-19
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| GEPROVAS | Strasbourg | 67000 | France |
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| ID | Term |
|---|---|
| D000086382 | COVID-19 |
| D012141 | Respiratory Tract Infections |
| ID | Term |
|---|---|
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
| D007239 | Infections |
| D014777 | Virus Diseases |
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| Between day 5 and day 10 |
| Evolution and complication | Number of deaths and patients admitted to hospital for worsening of respiratory signs of infection | Day 14 of infection |
| D018352 |
| Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |