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Irrational use of antibiotics is a one of the main health system problems,it leads to antibiotic resistance,increasing antibiotics side effects and the total cost. This study is a medication use evaluation study aims to evaluate intravenous clindamycin prescribing practice in critical care units in Alexandria Main University Hospital.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Clindamycin Injection | Drug | it is a clindamycin use evaluation study |
| Measure | Description | Time Frame |
|---|---|---|
| the number of prescriptions with appropriate indications of clindamycin will be counted during the retrospective observation of all prescriptions | appropriateness of clindamycin indication will be determined according to IDSA guidelines. | 1 month |
| Measure | Description | Time Frame |
|---|---|---|
| the number of prescriptions with duplication of therapy with clindamycin will be counted during the retrospective observation of all prescriptions | duplication of therapy means prescribing of clindamycin concurrently with another antibiotic to target the same microorganism. | 1 month |
| the number of patients who had diarrhea as a main side effect of clindamycin |
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Inclusion Criteria:
Exclusion Criteria:
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All adult patients admitted to critical care units and on clindamycin emperical therapy .
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Mdicine | Alexandria | Egypt |
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| ID | Term |
|---|---|
| D001424 | Bacterial Infections |
| ID | Term |
|---|---|
| D001423 | Bacterial Infections and Mycoses |
| D007239 | Infections |
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| ID | Term |
|---|---|
| D002981 | Clindamycin |
| ID | Term |
|---|---|
| D008034 | Lincomycin |
| D055231 | Lincosamides |
| D011759 | Pyrrolidines |
| D006573 | Heterocyclic Compounds, 1-Ring |
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diarrhea is a main side effect of clindamycin so in the study the number of patients who had diarrhea will be counted during the retrospective observation of all prescriptions |
| 1 month |
| the number of patients who had severe drug interactions with clindamycin | in the study the number of patients who severe clindamycin drugs interactions will be counted during the retrospective observation of all prescriptions | 1 month |
| Total clindamycin DDD defined daily doses and clindamycin defined daily doses per 1000 patients days. | Defined daily doses measurement of a drug is an indicator put by WHO , it indicates the consumption of this drug in a hospital or a department and defined daily doses per 1000 patients days indicates the consumption of this drug in relation to the total number of patients in a certain period of time. | 1 month |
| to calculate the total cost of clindamycin. | The cost of clindamycin treatment courses of all patients will be calculated in the Egyptian pound | 1 month |
| D006571 |
| Heterocyclic Compounds |
| D006027 | Glycosides |
| D002241 | Carbohydrates |