Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The purpose of this proof-of-concept study is to evaluate the safety, feasibility and acceptability of a breathwork workshop intervention in individuals with cannabis use disorder.
This study will test a 1-week breathwork workshop for treatment-seeking adults with a diagnosis of cannabis use disorder. The intervention consists of an enhanced breathing session with evocative music to facilitate experiencing non-ordinary states of consciousness, in addition to brief therapeutic interventions based on Motivational Interviewing and Mindfulness-based Relapse Prevention (MBRP). The primary aim is to test the acceptability, feasibility and safety of enhanced breathwork in a therapeutic framework for cannabis use disorder. In addition, the investigators seek to understand the phenomenology of breathwork that may explain any change related to addictive behaviors, as well as biological changes that occur during the breathwork session through heart rate variability and electroencephalography.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Breathwork group | Experimental | Treatment-seeking individuals with cannabis use disorder who will participate in the 1-week breathwork workshop. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Breathwork workshop | Behavioral | Participants will complete 1.5 hours of breathwork session in addition to a total of 6 hours of brief psychotherapeutic intervention in a span of 1 week. The therapy sessions will occur both before and after the breathing session. |
| Measure | Description | Time Frame |
|---|---|---|
| Acceptability of the breathwork session | Acceptability of the breathwork intervention through self-reported questionnaires. | One week after the breathing session. |
| Safety of the breathing session | Occurrence of adverse effects through a self-reported questionnaire. | 24 hours after the breathing session. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Cue Reactivity | Serial visual analogue scale for craving elicited by cannabis use. | From baseline to 1 month after the breathing session. |
| Change in Motivation to Quit | Measured with the "Stages of Change Readiness and Treatment Eagerness Scale." |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Silvia J Franco Corso, M.D | New York State Psychiatric Institute/ Columbia University Medical Center | Principal Investigator |
| Elias Dakwar, M.D | New York State Psychiatric Institute/ Columbia University Medical Center | Study Chair |
| Kate O'Malley, M.A | New York State Psychiatric Institute/ Columbia University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| New York State Psychiatric Institute | New York | New York | 10032 | United States |
Not provided
Not provided
Not provided
Not provided
Not provided
| Type | Date | Date Unknown |
|---|---|---|
| Release | Apr 21, 2026 | |
| Reset | May 15, 2026 | |
| Release | May 19, 2026 | |
| Reset | Jun 15, 2026 |
Not provided
Not provided
| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Apr 21, 2026 | May 15, 2026 | |||
| May 19, 2026 |
| ID | Term |
|---|---|
| D016739 | Behavior, Addictive |
| D019966 | Substance-Related Disorders |
| D002189 | Marijuana Abuse |
| ID | Term |
|---|---|
| D003192 | Compulsive Behavior |
| D007175 | Impulsive Behavior |
| D001519 | Behavior |
| D064419 | Chemically-Induced Disorders |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
| From baseline to 1 month after the breathing session. |
| Change in cannabis use | Changes in cannabis use as measured by the Timeline Followback. | From baseline to 1 month after the breathing session. |
| Phenomenology of breathwork #1 | Subjective experiences during the breathing session will be assessed with the 30-item Mystical Experience Questionnaire. | 24 hours after the breathing session |
| Phenomenology of breathwork #2 | Subjective experiences during the breathing session will be assessed with the Emotional Breakthrough Inventory. | Obtained 24 hours after the breathing session |
| Heart Rate Variability | Polar (H10) chest strap | Measured during breathing session |
| Electroencephalographic changes | Electroencephalograpy cap | Measured during breathing session |
| Jun 15, 2026 |
| D001523 |
| Mental Disorders |