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Patients and healthy volunteers will be scanned in order to test new sequences.
The aims of this study are to:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patient w/ Contrast | Other | Patients will add 15 minutes to their SOC MRI for research purposes |
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| Patient no contrast | Other | Patients will add 15 minutes to their SOC MRI for research purposes |
|
| Volunteer w/ contrast | Other | Volunteers undergo 1 research MRI for research purposes |
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| Volunteer no contrast | Other | Volunteers undergo 1 research MRI for research purposes |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MRI | Radiation | 1.5T or 3T MRI scanner (Siemens Medical Systems) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Conduct clinical protocol development and validation | Testing of new MRI pulse sequences will be performed for validation of potential new diagnostic capabilities. The MRI pulse sequences will be routinely performed along with clinically-validated and accepted pulse sequences for comparison of the novel sequences in human subjects (patients and healthy volunteers). Novel sequences will be performed in the accepted method with adjustment of settings to evaluate image qualities and normative values produced by the MRI machine. The resulting images provided by the novel sequences will be able to evaluated for diagnostic quality and to obtain comparison of possible improvements alongside clinically-validated MRI pulse sequences. | 5 years |
| Measure | Description | Time Frame |
|---|---|---|
| Demonstrate and train | Human subjects may be scanned utilizing MRI pulse sequences in the context of a clinical assessment for demonstrating of equipment or sequence function for training of MRI technologist. The sequence will be performed by a skilled technologist with the primary goal of providing information on proper utilizing of MRI hardware and software for technologist who are training and will be possibly utilizing these technique to provided safe and effective use of MRI systems and their software. |
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Inclusion Criteria:
• At least 18 years of age
Exclusion Criteria:
• When contrast is being administered: subjects with a GFR < 30 ml/min
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Emily Powell | Contact | 312.695.2956 | emily.powell@northwestern.edu | |
| Saira Jahangir | Contact | s-jahangir@northwestern.edu |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Northwestern University- Feinberg School of Medicine | Recruiting | Chicago | Illinois | 60611 | United States |
The research team may use the data obtained from this study for future institutionally approved studies not yet identified but conducted by Feinberg School of Medicine investigators. This means that information about you, including your name, date of birth, study data, etc. may be given to investigators not currently working on this study.
5 years
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| ID | Term |
|---|---|
| C090600 | gadobutrol |
| D012996 | Solutions |
| D007267 | Injections |
| ID | Term |
|---|---|
| D004364 | Pharmaceutical Preparations |
| D004333 | Drug Administration Routes |
| D004358 | Drug Therapy |
| D013812 | Therapeutics |
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If a research MRI is combined with a clinically ordered MRI, the research scan will add about 15 minutes to the clinical MRI procedure. If a research MRI is conducted during a separate visit, it is expected that the research-only MRI visit will last about 1-2 hours. An individual may voluntarily participate in the study on multiple occasions.
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| Gadavist 2Ml Solution for Injection | Drug | Arm 1 and Arm 3 subjects will undergo this intervention (Gadavist 2Ml solution) |
|
| 5 years |