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| Name | Class |
|---|---|
| Swiss Epilepsy Centre - Klinik Lengg | UNKNOWN |
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This study investigates whether the sense of agency is sensitive to self-regulation by means of EEG-based neurofeedback. During neurofeedback, the brain activity in response to a motor task is recorded in real-time and displayed back to the participants. The participants can therefore use this information to adapt their performance on the motor task.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Real neurofeedback | Experimental | The first arm will receive real neurofeedback. |
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| Sham neurofeedback | Sham Comparator | The second arm will receive sham neurofeedback. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Real Neurofeedback | Behavioral | During neurofeedback, the brain activity in response to a motor task is recorded in real-time and displayed back to the participants. |
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| Measure | Description | Time Frame |
|---|---|---|
| Change in Electrophysiological data, i.e., EEG power in alpha band | Brain activity | Before and immediately after neurofeedback |
| Change in Electrophysiological data, i.e., EEG power in theta band | Brain activity | Before and immediately after neurofeedback |
| Change in Electrophysiological data, i.e., EEG power in gamma band | Brain activity | Before and immediately after neurofeedback |
| Change in the subjective perception of the Sense of Agency, i.e., visual analog scale assessing how much control participants feel over the game | Behavioural performance in response to manipulation of the Sense of Agency (SoA) | Before and immediately after neurofeedback |
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| Measure | Description | Time Frame |
|---|---|---|
| Age in years | Baseline variable | Before neurofeedback |
| Sex (male/female) | Baseline variable | Before neurofeedback |
Inclusion Criteria (all):
Inclusion Criteria (patients):
Exclusion Criteria (all):
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| ETH Zurich | Recruiting | Zurich | Canton of Zurich | 8057 | Switzerland |
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| ID | Term |
|---|---|
| D000091323 | Psychogenic Nonepileptic Seizures |
| D004833 | Epilepsy, Temporal Lobe |
| ID | Term |
|---|---|
| D012640 | Seizures |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
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Two arms will be investigated. The first one will receive real neurofeedback. The second one will receive sham neurofeedback (comparator).
During sham neurofeedback, a signal which resembles the participant's brain activity is used instead of the actual brain activity.
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| Sham Neurofeedback | Behavioral | During sham neurofeedback, a signal which resembles the participant's brain activity is used instead of the actual brain activity. |
|
| Years of education | Baseline variable | Before neurofeedback |
| Medication status | Baseline variable, list of drugs currently in use by the participant | Before neurofeedback |
| Anxiety | Baseline variable assessed with the State-Trait Anxiety Inventory (STAI). Minimum value (20) = no anxiety. Maximum value (80) = high anxiety. | Before neurofeedback |
| Mood | Baseline variable assessed with a visual analog scale. Minimum value (0) = bad mood. Maximum value (100) = good mood. | Before neurofeedback |
| Sleep habits | Baseline variable assessed with the Pittsburgh Sleep Quality Index (PSQI). Minimum value (0) = good sleep quality. Maximum value (20) = poor sleep quality. | Before neurofeedback |
| Daily rate of cigarettes | Baseline variable assessed in number of cigarettes/day | Before neurofeedback |
| D013568 |
| Pathological Conditions, Signs and Symptoms |
| D004828 | Epilepsies, Partial |
| D004827 | Epilepsy |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D000073376 | Epileptic Syndromes |