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Pyogenic liver abscess is one of the most common visceral abscesses, its incidence is increasing worldwide. According to the previous literature, the mortality rate of pyogenic liver abscess is as high as 31% and become a serious social health problem. However, the data of prospective observational real-world studies are scarce and no relevant research of the liver histological change has been reported, so the long-term prognosis and the risk factors for pyogenic liver abscess are still unknown. Patients will be followed up prospectively for a period of 2 years and observed clinical prognosis (all-cause mortality, the recurrence rate, and the rehospitalization rate). The investigators will investigate the predictive value of clinical risk factors for clinical prognosis and establish clinical prediction models to predict the long-term prognosis of pyogenic liver abscesses.
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| Measure | Description | Time Frame |
|---|---|---|
| Proportion and causes of deaths within 2 years of discharge from hospital | Define the proportion and causes of deaths within 2 years of discharge from hospital for patients admitted to the Department for pyogenic liver abscesses. | 2 years |
| Proportion and causes of re-hospitalization within 2 years of discharge from hospital | Define the proportion and causes of re-hospitalization within 2 years of discharge from hospital for patients admitted to the Department for pyogenic liver abscesses. | 2 years |
| Measure | Description | Time Frame |
|---|---|---|
| The recurrence rate of pyogenic liver abscess | Development new liver abscess after clinical cure during the 2 years follow up period | 2 years |
| The number of participants with Histological Change in the Liver |
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Inclusion Criteria:
Exclusion Criteria:
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Patients older than 18 years of age admitted for pyogenic liver abscesses
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Xuyen Xu, MD | Contact | 020-62786539 | xuxuwen95@126.com | |
| Muye Xia, MD | Contact | +86 17665730806 | xiamuye@foxmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| NanFang Hospital of Southern Medical University | Recruiting | Guangzhou | Guangdong | 5100515 | China |
There is no plan to share IPD with other researchers except for those are directly involved with this study.
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| ID | Term |
|---|---|
| D046290 | Liver Abscess, Pyogenic |
| D008100 | Liver Abscess |
| D000038 | Abscess |
| D007239 | Infections |
| ID | Term |
|---|---|
| D018784 | Abdominal Abscess |
| D013492 | Suppuration |
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
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Take 10ml blood sample for each patient
Assessment of histological change in the liver by using ultrasonography or transient elastography during the 2 years follow up period
| 2 years |
| D007249 |
| Inflammation |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |