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| Name | Class |
|---|---|
| Peking University | OTHER |
| Xuanwu Hospital, Beijing | OTHER |
| Beijing Anzhen Hospital | OTHER |
| Beijing Tongren Hospital |
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Chronic obstructive pulmonary disease(COPD) is an incompletely reversible and progressive pulmonary disease characterized by airflow restriction, which is the third leading cause of death worldwide, accounting for 6% of all deaths worldwide. Acute exacerbation (AE) of COPD can accelerate the decline of lung function, worsening pulmonary symptoms, and increase the risk of death in patients. Health education, inhaled technical guidance training, individual self-management, psychological counseling, home oxygen therapy, nutritional support, and other comprehensive interventions can help improve the lung function of COPD patients, alleviate clinical symptoms, improve the quality of life. While a number of COPD applications have been developed, few provide comprehensive assessment and guidance for these kinds of patients. Therefore, the investigators aim to establish a bundle care mode based on the mode of "hospital-home-community-patient", clarify the impact of the management on prognosis, and evaluate the effect of mobile medical-assisted bundle management mode. In this randomized controlled trial(RCT), AECOPD patients will be divided into interventional or control groups randomly. Patients in the interventional group will receive mobile medication and standard of care at the same time (bundle care mode). While patients in the control group will receive standard of care only (traditional management mode). This study will be conducted to compare the effects of traditional and bundle care modes, and to formulate the implementation path and specifications of bundle care for AECOPD patients after discharge in China.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Interventional group | Experimental | Participants will be given mobile medical and bundle care |
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| Control group | Other | Participants will be given mobile medical and standard of care. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Mobile Medical and bundle management | Other | Based on the current follow-up management platform of respiratory disease, the WeChat official account will be designed and used to provide health education for patients, such as smoking cessation, reasonable diet, appropriate exercise, etc., and monitor some physiological indicators (such as body temperature, weight, the score of mMRC, etc.) and guide patients to standardize medication and pulmonary rehabilitation. |
| Measure | Description | Time Frame |
|---|---|---|
| Readmission rate due to acute exacerbation of COPD within one year | Collected within one year after discharge | One year |
| Measure | Description | Time Frame |
|---|---|---|
| The time interval from discharge to the next acute exacerbation of COPD | Collected within one year after discharge | One year |
| The times of acute exacerbation of COPD | Collected within one year after discharge |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Lin Yingxiang, PhD | Contact | 13611370119 | bjlin666@163.com |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29474094 | Background | Rothnie KJ, Mullerova H, Smeeth L, Quint JK. Natural History of Chronic Obstructive Pulmonary Disease Exacerbations in a General Practice-based Population with Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2018 Aug 15;198(4):464-471. doi: 10.1164/rccm.201710-2029OC. | |
| 28219878 | Background |
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| OTHER |
| Guang'anmen Hospital of China Academy of Chinese Medical Sciences | OTHER |
| Emergency General Hospital | OTHER |
| Beijing Jishuitan Hospital | OTHER |
| Beijing Luhe Hospital | OTHER |
| Beijing Shijingshan Hospital | UNKNOWN |
| Beijing Jingmei Group Hospital | UNKNOWN |
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|
| Mobile Medical and standard of care | Other | Based on the mobile medical, participants will receive advice on standard medication only. |
|
| One year |
| The score of subjective symptom | Collected within one year after discharge. We will use modified Medical Research Council (mMRC) Dyspnoea Scale, COPD Assessment Test (CAT), St. George's Respiratory Questionnaire (SGRQ),Hospital Anxiety and Depression Scale (HADS) and Borg scale to assecc. | One year |
| The changes of spirometry | Collected within one year after discharge. FEV1/FEV, FEV1 %pre,FVC, DLCO and RV/TLC etc will be collected. | One year |
| The changes of arterial blood gas analysis | Collected within one year after discharge. PaO2, PaCO2, BE, HCO3-, Lac, K+, Na+, Glu etc will be collected. | One year |
| The changes of percent of eosinophil count | Collected within one year after discharge | One year |
| Average annual medical cost | Collected within one year after discharge | One year |
| The types and proportions of adverse events occurred during using WeChat official account. | Collected within one year after discharge | One year |
| Compliance index | It includes drug treatment compliance, mastery of drug inhalation skills, smoking cessation, improvement of nutritional status, changes of mental health status, compliance and mastery of lung rehabilitation exercise, and patients' cognitive level of chronic obstructive pulmonary disease. | One year |
| Sobnath DD, Philip N, Kayyali R, Nabhani-Gebara S, Pierscionek B, Vaes AW, Spruit MA, Kaimakamis E. Features of a Mobile Support App for Patients With Chronic Obstructive Pulmonary Disease: Literature Review and Current Applications. JMIR Mhealth Uhealth. 2017 Feb 20;5(2):e17. doi: 10.2196/mhealth.4951. |
| ID | Term |
|---|---|
| D029424 | Pulmonary Disease, Chronic Obstructive |
| D008173 | Lung Diseases, Obstructive |
| ID | Term |
|---|---|
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D002908 | Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D059039 | Standard of Care |
| ID | Term |
|---|---|
| D019984 | Quality Indicators, Health Care |
| D011787 | Quality of Health Care |
| D006298 | Health Services Administration |
| D017530 | Health Care Quality, Access, and Evaluation |
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