SafeTy and Efficacy of Preventative CoVID Vaccines

SafeTy and Efficacy of Preventative CoVID Vaccines

The STOPCoV study is a decentralized study comparing COVID-19 vaccine specific antibody levels at 24 weeks after final vaccine dose. We plan to study the safety and immunogenicity of COVID-19 vaccine(s) in community dwelling persons 70 years and over relative to a younger group (aged 30 - 50 years).

This is a prospective observational study of a cohort of individuals aged 30-50 years and a cohort of individuals aged 70 years and over receiving the COVID-19 vaccine.

Participants will complete a questionnaire to determine eligibility. Eligible participants will complete and sign an e-consent and then be provided with a participant ID, log in information and password to the database portal, and then be enrolled into the study.

Participants will complete the study assessments (baseline questionnaire, post vaccine symptom e-diary monthly, check-in questionnaire and dried blood spot specimens)

Inclusion Criteria:

• Must be a resident of Ontario

Arm A:

• Individuals aged 70 and over
• Speak, read and understand English (or have a trusted individual to help with study procedures)
• Will receive a first or second dose of a COVID-19 vaccine at an Ontario vaccine distribution center. Individuals reaching the minimum age requirement by end of the recruitment calendar year are allowed to participate.

Arm B:

• Individuals between age 30-50 years
• Speak, read and understand English (or have a trusted individual to help with study procedures)
• Receive a first or second dose of a COVID-19 vaccine at an Ontario vaccine distribution center.

Exclusion Criteria:

• Not a resident of Ontario
• Individuals who are < 30 years or those 51-69 years.
• Those who are unable to complete the study protocols in English either alone or with the assistance of a trusted individual with an electronic device.
• Participants who do not receive any dose of the vaccine
• Participants who have already received both doses of the vaccine prior to enrolment.