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It is a retrospective study. Patients, who presented with either traumatic or general surgery emergencies, undergone exploratory laparotomy, had an open abdomen management and received Direct Peritoneal Resuscitation in addition to standard resuscitation will be considered as meeting the criteria to collect the data.
Due to the high volume of patient transfers from different facilities with difficult intra-abdominal pathologies and the high case-mix index at Westchester Medical Center, we see many patients who require re-operations and open abdominal management. Since July1st of 2020 we have been using DPR in addition to standard iv fluids on all patients who undergo open abdominal management and it is now standard of care at our facility. we plan to collect the data from all qualified subjects who received DRP since 7/1/2020 to 6/30/2022.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| there is no intervention involved in this study | Other | there is no intervention involved in this study. |
| Measure | Description | Time Frame |
|---|---|---|
| Post operative outcomes | intra abdominal infections and other complications | through out the hospitalization and 30 days after discharge. |
| Measure | Description | Time Frame |
|---|---|---|
| length of hospital stay | includes ICU stay, ventilator days and mortality. | post procedure to 30 days after discharge. |
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Inclusion Criteria:
Exclusion Criteria:
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Adult patients 18 and above, who presents with either traumatic or general surgery emergencies and undergone exploratory laparotomy had an open abdomen management and received DPR in addition to standard resuscitation will be considered as meeting the criteria to be in the study.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Anuritha Tirumani, MBBS | Contact | 914-493-3470 | anuritha.tirumani@wmchealth.org | |
| Abbas Smiley, MD | Contact | 914-493-3470 | abbas.smiley@wmchealth.org |
| Name | Affiliation | Role |
|---|---|---|
| Kartik Prabhakaran, MD | New York Medical College | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| New York Medical College | Recruiting | Valhalla | New York | 10595 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 20421025 | Background | Smith JW, Garrison RN, Matheson PJ, Franklin GA, Harbrecht BG, Richardson JD. Direct peritoneal resuscitation accelerates primary abdominal wall closure after damage control surgery. J Am Coll Surg. 2010 May;210(5):658-64, 664-7. doi: 10.1016/j.jamcollsurg.2010.01.014. | |
| 14599604 | Result | Zakaria el R, Hurt RT, Matheson PJ, Garrison RN. A novel method of peritoneal resuscitation improves organ perfusion after hemorrhagic shock. Am J Surg. 2003 Nov;186(5):443-8. doi: 10.1016/j.amjsurg.2003.07.006. |
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no plan as of now
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| ID | Term |
|---|---|
| D007416 | Intestinal Perforation |
| D007415 | Intestinal Obstruction |
| D000007 | Abdominal Injuries |
| ID | Term |
|---|---|
| D007410 | Intestinal Diseases |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
| D014947 | Wounds and Injuries |
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| 26169030 | Result | Crafts TD, Hunsberger EB, Jensen AR, Rescorla FJ, Yoder MC, Markel TA. Direct peritoneal resuscitation improves survival and decreases inflammation after intestinal ischemia and reperfusion injury. J Surg Res. 2015 Dec;199(2):428-34. doi: 10.1016/j.jss.2015.06.031. Epub 2015 Jun 18. |