Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The injuries induced by Human Papillomavirus (HPV) (anogenital condyloma mainly) are more frequent among transplanted patients due to their immunosuppression. These injuries are benign but they have a negative impact on the patients' quality of life. The initial treatment is topical and then surgical. The injuries can relapse, especially among transplanted patients.
The modification of the immunosuppressant treatment with a switch to mTOR inhibitors (mammalian Target Of Rapamycin) has shown its efficacy in preventing the recurrence of squamous cell carcinomas or treating Kaposi's disease.
By analogy, this therapeutic strategy can be sometimes put forward to transplanted patients with HPV-induced injuries.
The principal objective of this study is to describe the evolution of HPV-induced lesions in solid organ transplant patients.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| review of medical patient file | Other | The outcome measure is the evolution of HPV related lesions between :
|
| Measure | Description | Time Frame |
|---|---|---|
| Evolution of HPV related lesions in patient with switch | At one year of the switch by an inhibitor of mTOR then remotely of the switch (by tacking the last medical encounter) for the patients concerned by the switch. | at inclusion |
| Evolution of HPV related lesions in patient without switch | At one year of the first HPV related lesions care then remotely (by tacking the last medical encounter) for the patients without the switch. | at inclusion |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Patient transplanted with HPV-induced lesions from the DIVAT (Validated Transplantation Computerized Data) database for patients followed at the hospital Edouard Herriot
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Fanny BURON, MD | Hôpital Rdouard Herriot | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hôpital Edouard Herriot | Lyon | Auvergne-Rhône-Alpes | 69003 | France |
Not provided
Not provided
Not provided
Not provided