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| Name | Class |
|---|---|
| Mitacs | INDUSTRY |
| Neuro-Concept Inc. | UNKNOWN |
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The objectives of the study are to evaluate trunk task-oriented training combined with function electrical stimulation (FES/T-TOT) efficacy on sitting balance and functional independence, and to understand the mechanisms of neuroplasticity that would improve functional independence following FES/T-TOT in individuals with spinal cord injury.
After obtaining their consent, participants will undertake evaluations at different times:
Each assessment will be divided in 2 sessions and data will be collected over 2 days, at one session per day. The assessment will consist of:
After the initial assessment, the participants with spinal cord injury will realize 36 sessions of trunk task-oriented training alone or combined with function electrical stimulation (3 times a week for 12 weeks).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Trunk-oriented task combined with functional electrical stimulation training group | Experimental | This group will be formed with participants with spinal cord injury. This group will perform 12 weeks of trunk-oriented task training combined with functional electrical stimulation. |
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| Trunk-oriented task training group | Active Comparator | This group will be formed with participants with spinal cord injury. This group will perform 12 weeks of trunk-oriented task training. |
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| Control group | No Intervention | Healthy participants will be recruited based on the age and sex of the participants with spinal cord injury to realize clinical, biomechanical and cortical evaluations |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Trunk-oriented task training combined with functional electrical stimulation | Other | Training will consist to perform one hour of trunk task-oriented training combined with functional electrical stimulation (FES/T-TOT) specific for muscle strength and motor control. All training will be done seated without support with knees and hips flexed to 90 degrees. FES will be combined with functional and non-functional tasks to work functionality and muscle strengthening. Each training session will consist on the fulfilment of two functional tasks (as reaching) and two non-functional tasks (as push-up movement) from a battery of postural control exercises. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Function in Sitting Test | This test evaluates the sitting balance via 14 everyday functional activities rated from 0 to 4 according to the reactions of the participants. | Before and after the 12-week trainings and 1-month follow-up |
| Change in modified Functional Reach Test | This test evaluates the ability for each participant to realize a lateral and anterior trunk flexion in order to observe the maximum distance reached. | Before and after the 12-week trainings and every 4-weeks during the training period |
| Measure | Description | Time Frame |
|---|---|---|
| Change in EMG activation pattern of electromyographic activity of muscles in the trunk | during reaching and pointing tasks | Before and after the 12-week trainings and 1-month follow-up |
| Change in the center of pressure excursion |
| Measure | Description | Time Frame |
|---|---|---|
| Physical Activity Recall Assessment for People with Spinal Cord Injury (questionnaire) | This interview will capture all physical activity information over the previous 3 days. Eight periods of day will be screened (morning routine, breakfast, morning, lunch, afternoon, dinner, evening, evening routine). This test allows us to verify if the intensity of daily physical activity of each participant will be constant during the intervention. |
FOR PARTICIPANTS WITH SPINAL CORD INJURY
Inclusion Criteria:
Exclusion Criteria:
FOR CONTROL PARTICIPANTS
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Dorothy Barthélemy, PhD, PT | Contact | 514-343-7712 | dorothy.barthelemy@umontreal.ca | |
| Charlotte Pion, PhD, Kin | Contact | 438-490-8512 | charlotte.pion@umontreal.ca |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Neuro-Concept Inc | Recruiting | Montreal | Quebec | Canada |
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| Trunk-oriented task training alone | Other | The SCI participants who will perform T-TOT training alone will have to perform the same exercises as explained in the previous section (two functional tasks and two non-functional tasks) but they will not receive any functional electrical stimulation. Training will consist to perform one hour of trunk task-oriented training (T-TOT) specific for muscle strength and motor control. All training will be done seated without support with knees and hips flexed to 90 degrees. Each training session will consist on the fulfilment of two functional tasks (as reaching) and two non-functional tasks (as push-up movement) from a battery of postural control exercises. |
|
during reaching and pointing tasks
| Before and after the 12-week trainings and 1-month follow-up |
| Modification of the excitability of the reticulospinal pathway using the acoustic startle response | A tone will be triggered just before the reaching movement. The EMG responses of trunk muscles will be analyzed. | Before and after the 12-week trainings and 1-month follow-up |
| Modification of the excitability of the vestibulospinal pathway using galvanic vestibular stimulation | Vestibular responses induced by GVS will be identified in the trunk muscles | Before and after the 12-week trainings and 1-month follow-up |
| Before and after the 12-week trainings |
| Change in quality of life using World Health Organization Quality of Life with disabilities module (WHOQOL-BREF) | This questionnaire consists in 39 questions about participant feelings. | Before and after the 12-week trainings and 1-month follow-up |
| Change in quality of life using Short-Form 36 questionnaire | The questionnaire consists in 36 questions about 8 domains: physical functioning, role functioning-physical, bodily pain, general health, vitality, social functioning, role functioning-emotional and mental health | Before and after the 12-week trainings and 1-month follow-up |
| Change in the Quality of life index | This questionnaire consists in 37 questions about 4 domains: health and functioning, psychological/spiritual, social and economic, and family. | Before and after the 12-week trainings and 1-month follow-up |
| Change in functional independence using Spinal Cord Independence Measure questionnaire | This questionnaire consists in evaluation of self-care, respiration and sphincter management, and a participant's mobility abilities. | Before and after the 12-week trainings and 1-month follow-up |
| Neuromobility lab | Enrolling by invitation | Montreal | Quebec | Canada |
| ID | Term |
|---|---|
| D013119 | Spinal Cord Injuries |
| ID | Term |
|---|---|
| D013118 | Spinal Cord Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D020196 | Trauma, Nervous System |
| D014947 | Wounds and Injuries |
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