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Critically ill patients experience a severe physical disease, associated with a psychotrauma, which may lead to post-traumatic stress disorder (17 to 30% of patients after critical illness) and persistent symptoms of anxiety and depression. RESIREA study will study psychodrama, resilience and factors associated with resilience in patients previously included in the NUTRIREA-3 randomized controlled trial designed to compare standard calorie and protein feeding complying with guidelines to low-calorie low-protein feeding in a well-defined group of severely ill ICU patients requiring at least MV and vasoactive drugs.
Social demographic data (gender, age, marital status, psychological information and medical background) and medical data (severity of the disease, duration of ICU stay, SOFA score) will be collected, as for the NUTRIREA-3 trial.
Before leaving the ICU, patient who agreed to participate to the NUTRIREA 3 study were asked to participate to the RESIREA study.
Patients will be called by phone by a psychologist 3 months after their inclusion in the NUTRIREA-3 trial to complete the SF-36 score. Then, they will be asked to confirm their participation to the RESIREA study by completing four additional questionnaires (post-trauma stress disorder: IES-R; Resilience: CD-RISC; Social support: MSPSS; Perception of the disease: B-IPQ). If the patient does not respond to the phone call at the first time, he/she will be contacted again within a period of 2 weeks maximum (1 call/day). If the patient remains unreachable, he/she will be considered as lost for the study. Patients will be called again 12 months after their inclusion in the NUTRIREA-3 trial and will be asked to complete the five questionnaires (SF-36, IES-R, CD-RISC, MSPSS and B-IPQ).
During this last phone call, 40 patients will be asked to a third interview by phone. These patients will be spotted thanks to their score at the IES-R and CD-RISC. This interview of 30 to 45 minutes will be planned within 15 days after the T12 call and recorded. This semi structured interview will be lead by an experienced clinical psychologist and follow 4 main topics :
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| Measure | Description | Time Frame |
|---|---|---|
| Proportion of patients with post-traumatic disorders | IES-R scale | 3 months after ICU stay |
| Measure | Description | Time Frame |
|---|---|---|
| Proportion of resilient patients | CD-RISC score > 80 | 3 and 12 months after ICU stay |
| proportion of patients with impaired Quality of life | SF-36 score |
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Inclusion Criteria:
Exclusion Criteria:
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Patients included in the NUTRIREA3 study will be contacted by phone calls to complete the quality of life scale (SF-36) 3 and 12 months after inclusion in the trial. Patients included in 24 of the 61 ICUs participating to the NUTRIREA-3 trial will be asked to participate to the RESIREA study at the 3-month phone call, by completing 4 additional questionnaires (IES-R, CD-RISC, MSPSS, B-IPQ), 3 and 12 month after their inclusion in the NUTRIREA-3 trial.
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| Name | Affiliation | Role |
|---|---|---|
| Jean REIGNIER, PhD | Nantes University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Amiens Picardie nord | Amiens | 80054 | France | |||
| CHU Amiens Picardie sud |
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| ID | Term |
|---|---|
| D012769 | Shock |
| D016638 | Critical Illness |
| D013313 | Stress Disorders, Post-Traumatic |
| D000067073 | Psychological Trauma |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D020969 | Disease Attributes |
| D040921 | Stress Disorders, Traumatic |
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| 3 and 12 months after ICU stay |
| Proportion of patients with post-traumatic disorders | IES-R | 12 months after ICU stay |
| Social support | IES-R | 3 and 12 months after ICU stay |
| perception of the disease | MSPSS score | 3 and 12 months after ICU stay |
| Amiens |
| 80054 |
| France |
| CHU Angers | Angers | 49100 | France |
| CH Angoulême | Angoulême | 16959 | France |
| CH Annecy Genevois | Annecy | 74374 | France |
| CH Argenteuil | Argenteuil | 95100 | France |
| CHU Jean Minjoz | Besançon | 25030 | France |
| CH de Béthune | Béthune | 62408 | France |
| CH Chartres Louis Pasteur | Chartres | 26860 | France |
| CHU Gabriel Montpided | Clermont-Ferrand | 63003 | France |
| CH Dieppe | Dieppe | 76202 | France |
| APHP - Hôpital Raymond Poincaré | Garches | 92380 | France |
| CHD Vendée | La Roche-sur-Yon | 85025 | France |
| CH du Mans | Le Mans | 72037 | France |
| CH de Lens | Lens | 62300 | France |
| CHR- Roger Salengro | Lille | 59037 | France |
| Hôpital Edouard Herriot | Lyon | 69437 | France |
| CHU de Nantes | Nantes | 44000 | France |
| APHP - Hôpital Cochin | Paris | 75014 | France |
| CH de Bigorre | Tarbes | 65013 | France |
| CHRU Bretonneau | Tours | 37044 | France |
| CHU de Valenciennes | Valenciennes | 59300 | France |
| CHBA - Vannes Auray | Vannes | 56017 | France |
| D000068099 | Trauma and Stressor Related Disorders |
| D001523 | Mental Disorders |