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An open-label, multiple-dosing, two-arms, one-sequence study to evaluate the safety and pharmacokinetics after co-administration of UIC201601 and UIC201602 in healthy male volunteers.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Treatment A | Experimental |
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| Treatment B | Experimental |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| UIC201602 and co-administration of UIC201601 and UIC201602 | Drug |
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| Measure | Description | Time Frame |
|---|---|---|
| Plasma pharmacokinetics(AUCss,Ï„) of UIC201602 | Area under the serum drug concentration-time curve within a dosing interval at steady state | 0 hour to 24 hours after Day 14 and Day 49 administration |
| Plasma pharmacokinetics(Css,max) of UIC201602 | Maximum concentration of drug in serum at steady state | 0 hour to 24 hours after Day 14 and Day 49 administration |
| Plasma pharmacokinetics(AUCss,Ï„) of UIC201601 | Area under the serum drug concentration-time curve within a dosing interval at steady state | 0 hour to 24 hours after Day 7 and Day 35 |
| Plasma pharmacokinetics(Css,max) of UIC201601 | Maximum concentration of drug in serum at steady state | 0 hour to 24 hours after Day 7 and Day 35 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Janghee Hong, M.D.,Ph.D. | Chungnam National University Hospital | Principal Investigator |
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| UIC201601 and co-administration of UIC201601 and UIC201602 | Drug |
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