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The study aims to evaluate the efficacy of ridge preservation with collagen sponge or collagen membrane in combination with collagenated bovine bone mineral in extraction sockets of periodontally diseased teeth.
The study aims to evaluate the changes of clinical and radiographic outcomes following ridge preservation with collagen sponge or collagen membrane in combination with collagenated bovine bone mineral in extraction sockets of periodontally diseased teeth. The included patients will be randomized into two groups. The patients in control group will be treated with collagen membrane + collagenated bovine bone mineral, and those in the test group will be treated with collagen sponge + collagenated bovine bone mineral. The horizontal width of ridge, the vertical height of ridge at the buccal and palatal/lingual plates, width of keratinized tissue and thickness of mucosa will be measured before surgery and at 6 months postoperatively.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Collagen Membrane | Active Comparator | ridge preservation with collagen membrane + collagenated bovine bone mineral |
|
| Collagen Sponge | Experimental | ridge preservation with collagen sponge + collagenated bovine bone mineral |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| alveolar ridge preservation | Procedure | Alveolar ridge preservation and augmentation commonly are performed immediately after tooth extraction to preserve or increase ridge volume within or beyond the skeletal envelope that exists at the time of extraction. |
| Measure | Description | Time Frame |
|---|---|---|
| change from baseline horizontal width of ridge at 6 months | horizontal width of ridge at 1, 3, 5mm below crest | baseline, at 6 months |
| change from baseline vertical height of ridge at 6 months | vertical height of ridge at the buccal and palatal/lingual plates | baseline, at 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| width of keratinized tissue | measured from the MGJ to the mucosa margin at the mid-buccal aspect using a periodontal probe | at 6 months |
| thickness of mucosa | measured at the mid-buccal aspect using an endodontic file with a rubber stop |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Weida Li, master | Contact | 0571-87219287 | kyb@zjkq.com.cn |
| Name | Affiliation | Role |
|---|---|---|
| Peihui Ding, Doctor | The Affiliated Stomatology Hospital of Zhejiang University School of Medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The Affiliated Stomatology Hospital of Zhejiang University School of Medicine | Recruiting | Hangzhou | Zhejiang | China |
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| ID | Term |
|---|---|
| D010518 | Periodontitis |
| ID | Term |
|---|---|
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
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| at 6 months |
| postoperative pain | using a visual analog scale (VAS) ranging from 0 to 10 (0 = no pain and 10 = worst pain imaginable) | at 2 weeks |