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| Name | Class |
|---|---|
| Alberta Innovates Health Solutions | OTHER |
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Implementation of an evidence-based and best practices acute RRT pathway aiming to decrease acute RRT program and healthcare systems costs while improving important patient-reported outcomes.
Providing acute dialysis to critically ill patients in ICU settings is resource and cost intensive. The daily costs of acute dialysis can range from $528/day for intermittent hemodialysis to $865/day for continuous renal replacement therapy. Providing acute dialysis in ICU settings requires a specialized team of nurses, educators, physicians and stakeholders to ensure its safe and effective prescription and delivery. Acute dialysis is typically delivered to some of the most acutely ill patients admitted to the ICU to support organ function and sustain life.
At present, there is not a standardized approach to the prescription and delivery of acute dialysis therapy in ICUs across Alberta. The DIALYZING WISELY program will implement a standardized approach to the delivery of best practices for acute dialysis therapy to all patients who receive treatment across ICUs in Alberta.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ICU patients receiving renal replacement therapy | All patients in participating ICU's receiving CRRT or IRRT during the study period |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| KPI reports | Other | Quarterly |
|
| Measure | Description | Time Frame |
|---|---|---|
| Key performance indicators (KPI) | Changes in acute KPIs | Throughout intervention period up to 3 years |
| Health system costs | Acute RRT and healthcare systems costs | 3 years |
| Measure | Description | Time Frame |
|---|---|---|
| Length of renal replacement therapy | Length of time patient receives RRT during their ICU stay | 3 years |
| ICU and hospital lengths of stay | Number of days patient spends in the ICU and hospital |
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Inclusion Criteria:
Patient in one of 15 adult and 3 pediatric intensive care units in Alberta Receive acute RRT as part of their usual clinical care during the intervention period
Exclusion Criteria:
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All patients from 15 adult and 3 pediatric Alberta ICUs who receive acute RRT as part of their usual clinical care during the intervention period
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Dawn Opgenorth, RN | Contact | 780 492-4698 | dawno@ualberta.ca | |
| Oleksa Rewa, MD | Contact | rewa@ualberta.ca |
| Name | Affiliation | Role |
|---|---|---|
| Oleksa Rewa, MD | University of Alberta | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Peter Lougheed Centre | Recruiting | Calgary | Alberta | T1Y 6J4 | Canada |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36384465 | Derived | Opgenorth D, Bagshaw SM, Lau V, Graham MM, Fraser N, Klarenbach S, Morrin L, Norris C, Pannu N, Sinnadurai S, Valaire S, Wang X, Rewa OG. A study protocol for improving the delivery of acute kidney replacement therapy (KRT) to critically ill patients in Alberta - DIALYZING WISELY. BMC Nephrol. 2022 Nov 16;23(1):369. doi: 10.1186/s12882-022-02990-6. |
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| ID | Term |
|---|---|
| D058186 | Acute Kidney Injury |
| ID | Term |
|---|---|
| D051437 | Renal Insufficiency |
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
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| Prescriber reports | Other | Individualized prescriber reports for acute RRT initiation patterns along with targeted education to ensure that align with best evidence-based practices |
|
| 3 years |
| ICU and 90 day mortality | number of patients who die before ICU discharge or within 90 days of ICU stay | 3 years |
| Rates of RRT dependence at 90 days | number of patients who are receiving RRT at 90 days after ICU stay | 3 years |
| Foothills Medical Centre | Recruiting | Calgary | Alberta | T2N 2T9 | Canada |
|
| Rockyview General Hospital | Recruiting | Calgary | Alberta | T2V 1P9 | Canada |
|
| Alberta Children's Hospital | Recruiting | Calgary | Alberta | T3B 6A8 | Canada |
|
| South Health Campus | Recruiting | Calgary | Alberta | T3M 1M4 | Canada |
|
| Royal Alexandra Hospital | Recruiting | Edmonton | Alberta | T5H 3V9 | Canada |
|
| Misericordia Community Hospital | Recruiting | Edmonton | Alberta | T5R 4H5 | Canada |
|
| Manzankowski Alberta Heart Institute | Recruiting | Edmonton | Alberta | T6G 2B7 | Canada |
|
| Stollery Children's Hospital | Recruiting | Edmonton | Alberta | T6G 2B7 | Canada |
|
| University of Alberta Hospital | Recruiting | Edmonton | Alberta | T6G-2B7 | Canada |
|
| Grey Nuns Community Hospital | Recruiting | Edmonton | Alberta | T6L 5X8 | Canada |
|
| Grande Prairie Regional Hospital | Recruiting | Grande Prairie | Alberta | T8V 4B1 | Canada |
|
| Chinook Regional Hospital | Recruiting | Lethbridge | Alberta | T1J 1W5 | Canada |
|
| Red Deer Regional Hospital Centre | Recruiting | Red Deer | Alberta | T4N 4E7 | Canada |
|
| Sturgeon Community Hospital | Recruiting | St. Albert | Alberta | T8N 6C4 | Canada |
|
| D005261 |
| Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |