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The purpose of this study is to assess the effect of propofol induced general anaesthesia on the ST-segment of the electrocardiogram. This will be realised by retrospectively analysing the ECG-recordings from adult patients undergoing any treatment at the Catheterisation Laboratory. The ST-segment and other ECG measurements from induction of anaesthesia up to 20 minutes later, will be assessed and compared to the baseline values of the respective segments acquired before injecting propofol. It is essential in this study to exclude any patients burdened with the diagnosis, suspicion or family history of Brugada syndrome.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| non-Brugada population | Adult patients who underwent general anaesthesia (with propofol as induction agent) at the catheterisation laboratory of the UZ Brussel |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Observational study | Other | Retrospective data-analysis |
|
| Measure | Description | Time Frame |
|---|---|---|
| ST-segment variations after propofol administration. | Determine ST-segment variations in mm (either augmentation or suppression) on the ECG in the 20 minute period after administration of propofol in comparison to the baseline ECG | Baseline ECG will be measured before administration of propofol. ECG will be measured in the 20 minutes following administration of propofol |
| Measure | Description | Time Frame |
|---|---|---|
| Additional ECG-segment variations after propofol administration | Assess additional ECG-segments measurements in mm and ms from the ECGs recorded. These include Jp- (mm), QRS- (ms), T(p-e)-segments (ms) and the T(p-e)/QT ratio. | Baseline ECG will be measured before administration of propofol. ECG will be measured in the 20 minutes following administration of propofol |
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Inclusion Criteria:
Exclusion Criteria:
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Adult patients who underwent a surgical procedure under propofol-based general anaesthesia in the CathLab of UZB.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Universitair Ziekenhuis Brussel | Brussels | Brussels Capital | 1090 | Belgium |
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| ID | Term |
|---|---|
| D019370 | Observation |
| ID | Term |
|---|---|
| D008722 | Methods |
| D008919 | Investigative Techniques |
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