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This study is a retrospective work involving the review of patients who were scheduled for VP or LP shunt in Siriraj Hospital, Mahidol University, Thailand. The sample size calculation was based on the rule of thumbs of the logistic regression comprising 18 risk factors. The incidence of post-induction hypotension according to our institution's pilot study November 2019-January 2020) was 47%. With 10% addition for missing data and other possible reasons, the sample size was 426. The primary objective of the study is to report the factors associated with post-induction hypotension in iNPH patients undergoing VP or LP shunt procedures. Our secondary objective is to determine the incidence of post-induction hypotension in these patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Hypotensive group | Hypotenson is defined as systolic blood pressure (SBP) < 80 mmHg or a drop more than 20% from baseline SBP for longer than 10 minutes or a drop that requires treatment either vasopressor or inotropic drugs. |
| |
| Non-hypotensive group | The pateints who did not develop hypotensive episodes as aforementioned. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ehedrine Norepineprine | Drug | No interventions required considering that this was a retrospective study. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Factors associated with post-induction hypotension in iNPH patients undergoing VP or LP shunt procedures | Risk factors associated with post-induction hypotension after administration of anesthetic agents | 9 months |
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Inclusion Criteria:
Exclusion Criteria:
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- Elective cases of iNPH scheduled for VP and LP shunt whose medical records were acquired from the hospital's central database.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Anesthesiology Department | Bangkok | 10700 | Thailand |
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