The purpose of this study is to map comfort over the full wear day in established, asymptomatic, soft CL wearers who are refit in Total30 Sphere CLs.

Contact lens (CL) wearers frequently face eye discomfort symptoms, especially towards the end of the wear day. This burdensome discomfort can unfortunately cause patients to remove their CLs before their desired wear time. While comfortable wear times vary from patient to patient, Terry et al. has suggested that patients should be able to comfortably wear their CLs for at least 12 hours per day for at least 6 days per week. Nevertheless, the literature currently lacks sufficient data to comment fully on the full day wear experience, which for many patients may be 16 or more hours per day, especially if they have demanding careers. One CL that has the potential to allow for all day comfort is the Total30 Sphere CLs, which is a new water gradient, monthly CL aimed at delivering all day comfort and visual performance. Thus, the purpose of this study is to map comfort over the full wear day in established, asymptomatic, soft CL wearers who are refit in Total30 Sphere CLs. These data are not only important for judging the performance of Total30 Sphere CLs, but they will provide some of the first insights into the full day CL wearing experience over one month.

Inclusion Criteria:

• Current contact lens wearers who have 20/20 visual acuity or better
• Minimally symptomatic as based upon Contact Lens Dry Eye Questionnaire scores (≤10)
• Astigmatism better than or equal to 0.50 D in each eye
• Must have regularly worn 2 week or monthly contact lenses within the past 6 months
• Must provide a glasses prescription that is is less than 3 years old
• Willing to start wearing their contact lenses between 6:00 AM and 8:00 AM and wear their contact lenses until 11:00 PM each day

Exclusion Criteria:

• Past or Current hard CL use
• Any known systemic health conditions that are thought to alter tear film physiology
• History of viral eye disease
• History of ocular surgery
• History of severe ocular trauma
• Active ocular infection or inflammation
• Currently using isotretinoin-derivatives
• Currently using ocular medications
• Currently using rewetting drops or artificial tear
• Pregnant or breast feeding

Adult, 18- to 45-year-old, contact lens wearers who had 20/20 visual acuity or better and who were minimally symptomatic contact lens wearers were recruited. This was a single arm study, so no baseline analyses were performed.

Each participant was enrolled in this clinical trial for 1 month. The trial consisted of 3 in person visits (baseline, 1 week, and 1 month).

Subjects were seen by an eye care professional three different times during the 1 month study. They were put through standard eye exam measures and contact lenses were thoroughly checked for comfort prior to distribution.