Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
An unanticipated difficult laryngoscopy is associated with serious airway-related complications. The investigators developed a deep learning-based model that predicts a difficult laryngoscopy (Cormack-Lehane grade 3-4) from a cervical spine lateral X-ray using data from 14,135 patients undergoing thyroid surgery. This model showed excellent predictive performance, which was higher than that of other deep learning architectures. In this study, the investigators prospectively validate the model for predicting a difficult laryngoscopy and compare predictive power with clinical airway evaluation.
Predicting a difficulty of a laryngoscopy is important for patient safety, as an unanticipated difficult laryngoscopy is associated with serious airway-related complications, such as brain damage, cardiopulmonary arrest, or death. Although clinical predictors, such as the modified Mallampati classification, thyromental distance, inter-incisor gap, and the upper lip bite test, are used for airway evaluation in clinical practice, these indicators have low sensitivity and large inter-assessor variability and require patient cooperation.
The investigators developed a deep learning-based model that predicts a difficult laryngoscopy from a cervical spine lateral X-ray using data from 14,135 patients undergoing thyroid surgery. And this study is under submission.
This deep learning model showed the highest performance in predicting difficult laryngoscopy compared to other deep learning models (VGG-Net, ResNet, Xception, ResNext, DenseNet, and SENet) with a sensitivity of 95.6%, a specificity of 91.2%, and an area under ROC curve (AUROC) of 0.972.
However, as the model was a retrospective design using existing medical records, the presence or absence of cricoid pressure to obtain the optimal laryngoscopy was not evaluated, and not compared with airway evaluations.
In this study, the investigators prospectively validate the model for predicting a difficult laryngoscopy and compare predictive power with clinical airway evaluation. If this study prospective confirm our results, this approach can be helpful in improving patient safety and preventing airway-related complications through objective and accurate airway evaluation.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| A deep learning model for predicting a difficult laryngoscopy based on a cervical spine lateral X-ray image | Diagnostic Test | The deep learning model uses the input of preprocessed C-spine lateral X-ray images and outputs the level of difficulty of a laryngoscopy. The easy laryngoscopy is defined as a combination of the Cormack-Lehane grades 1-2 and the difficult laryngoscopy is defined as a combination of grades 3-4. In addition, before general anesthesia, airway evaluations related to the difficulty of laryngoscopy are performed and the results are compared with the actual level of difficulty. |
| Measure | Description | Time Frame |
|---|---|---|
| The area under the receiver operating characteristic curve of deep learning model and airway evaluations for predicting a difficult laryngoscopy. | Difficult laryngoscopy definition: Cormack-Lehane grade 3 or 4 . Airway evaluations: Inter-incisor gap (millimeter), thyromental distance (millimeter), thyromental height (millimeter), sternomental distance (millimeter), and modified Mallampati class | during induction of anesthesia |
| Measure | Description | Time Frame |
|---|---|---|
| The area under the receiver operating characteristic curve of deep learning model and airway evaluations for predicting a difficult intubation. | Difficult intubation: Intubation Difficulty Scale (score) | during induction of anesthesia |
| Other Performances for predicting a difficult laryngoscopy of deep learning model. |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Patients who undergoing thyroid surgery under general anesthesia
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Hye-yeon Cho, MD | Contact | +82-10-3808-7110 | bdbd7799@gmail.com | |
| Hyung-Chul Lee, MD, PhD | Contact | vital@snu.ac.kr |
| Name | Affiliation | Role |
|---|---|---|
| Hyung-Chul Lee | Seoul National University Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Seoul National University Hospital | Recruiting | Seoul | Select A State Or Province | 03080 | South Korea |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23242753 | Background | Cook TM, MacDougall-Davis SR. Complications and failure of airway management. Br J Anaesth. 2012 Dec;109 Suppl 1:i68-i85. doi: 10.1093/bja/aes393. | |
| 21948956 | Background | Lundstrom LH, Vester-Andersen M, Moller AM, Charuluxananan S, L'hermite J, Wetterslev J; Danish Anaesthesia Database. Poor prognostic value of the modified Mallampati score: a meta-analysis involving 177 088 patients. Br J Anaesth. 2011 Nov;107(5):659-67. doi: 10.1093/bja/aer292. Epub 2011 Sep 26. |
| Label | URL |
|---|---|
| VGG-Net | View source |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
sensitivity (percent), specificity(percent), Positive predictive value(percent), Negative predictive value (percent), F1-score, and balanced accuracy. |
| during induction of anesthesia |
| 31922378 | Background | De Cassai A, Boscolo A, Rose K, Carron M, Navalesi P. Predictive parameters of difficult intubation in thyroid surgery: a meta-analysis. Minerva Anestesiol. 2020 Mar;86(3):317-326. doi: 10.23736/S0375-9393.19.14127-2. Epub 2020 Jan 8. |
| ResNet | View source |
| Xception | View source |
| ResNext | View source |
| DenseNet | View source |
| SENet | View source |
| ID | Term |
|---|---|
| D013959 | Thyroid Diseases |
| ID | Term |
|---|---|
| D004700 | Endocrine System Diseases |
Not provided
Not provided