Interest of a highly cross-linked polyethylene acetabular component doped with vitamin E in total hip arthroplasty of the young and active subject.

A single-centre, prospective, randomised, single-blind, comparative study of two parallel groups of patients undergoing total hip arthroplasty:

• Group 1: Prosthesis with a second-generation ceramic-on-highly cross-linked polyethylene (CoPXE) couple.
• Group 2: Prosthesis with ceramic-on-ceramic (CoC) torque.

Inclusion Criteria:

• Patient aged 18 to 65 years,
• Who have signed their consent to participate in the study,
• For whom an indication for total hip arthroplasty has been given

Exclusion Criteria:

• History of hip surgery
• Indication for a dual mobility prosthesis (obese patient, dynamic spino-pelvic anomaly)
• Hip dysplasia
• Inflammatory rheumatic disease or any other progressive concomitant condition that may impact the patient's vital or functional prognosis
• Sequelae of neurological disease or stroke
• Pregnant or breastfeeding women
• Mental deficiency or any other reason that may hinder the understanding or the strict application of the protocol
• Patient likely not to return for follow-up visits
• Patient already included in another therapeutic study protocol
• Patient under court protection, guardianship or curatorship.