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Systemic sclerosis is an autoimmune disease in which the hand is responsible for 75% of the overall disability. Management is based on systemic treatments combined with kinesitherapy aimed at maintaining joint amplitudes, improving muscle strength and preventing stiffness. The aim of this study is to describe and compare the average spontaneous and attempted reduction range of motion limitations between the dominant and contralateral hand.
Systemic sclerosis is an autoimmune disease in which the hand is responsible for 75% of the overall disability. In case of limitation, the level of skin fibrosis, Raynaud's syndrome and its complications, the search for painful joints with or without synovitis, and the presence of calcifications must therefore be assessed. Management is based on systemic treatments combined with kinesitherapy aimed at maintaining joint amplitudes, improving muscle strength and preventing stiffness. No study to date has compared the functionality of one hand to the other. The hypothesis is that there is a difference in range of motion limitations between the dominant hand and the contralateral hand.
Patients in the active file of the Internal Medicine A department of the Limoges University Hospital who meet the inclusion criteria will be offered the study by telephone. Patients wishing to participate will be given an appointment on a dedicated consultation slot. During this visit, Patients will be given an information note and their consent will be collected. The study examinations will be performed and the questionnaire completed. At the end of this visit, the study will be completed for the patient.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| moderate Scleroderma | Experimental | Patients with Cochin hand score less than or equal to 16 |
|
| severe Scleroderma | Experimental | Patients with Cochin hand score greater than 16 |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Measurement of joint amplitudes | Diagnostic Test | Measurement of joint amplitudes by goniometry of the MCP, IPP, IPD for 2, 3, 4 and 5th radii, 1st commissure spacing and Kapandji score for the thumb |
| Measure | Description | Time Frame |
|---|---|---|
| Measurement of joint amplitudes | Measurement of joint amplitudes by goniometry | at inclusion |
| Measure | Description | Time Frame |
|---|---|---|
| Digital skin score | Measure with modified Rodnan skin score. The value of this score varies from 0 (no cuntaneous sclerosis) to 51(severe cutaneous sclerosis). | at inclusion |
| Digital pressure | use of Finger Systolic Blood Pressure Index (FBPI) proposed by Blaise et al. |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU de Limoges | Limoges | 87042 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38526006 | Result | Fourmond S, Parreau S, Dumonteil S, Verdie-Kessler C, Ly KH, Lacroix P, Fauchais AL, Bernard P, Palat S. The functional disabilities of the dominant and opposite hands in patients with systemic sclerosis. Clin Exp Rheumatol. 2024 Aug;42(8):1665-1668. doi: 10.55563/clinexprheumatol/db7upl. Epub 2024 Mar 19. |
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| ID | Term |
|---|---|
| D012595 | Scleroderma, Systemic |
| D045743 | Scleroderma, Diffuse |
| ID | Term |
|---|---|
| D003240 | Connective Tissue Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D012871 | Skin Diseases |
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Prospective, descriptive and comparative, monocentric pilot study
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| at inclusion |
| Number of digital ulcers | at inclusion |
| Number of subcutaneous calcifications | at inclusion |
| Visual Analog Score for pain | Score varie from 0 (no pain) to 10 (worst pain possible) | at inclusion |
| number of painful joints | at inclusion |