Cohort Study for the Assessment of Long-term Impact of COVID-19 Among Moderate and Severe COVID-19 Patients in Brazil

Cohort Study for the Assessment of Long-term Impact of COVID-19 Among Moderate and Severe COVID-19 Patients in Brazil

The present prospective cohort study aims to assess factors associated with of one-year health-related quality of life and physical, cognitive and mental health outcomes among adult survivors of hospitalization for COVID-19. Adult patients requiring hospitalization due to COVID-19 disease will be followed through structured and centralized telephone interviews performed at 3, 6, 9 and 12 months after enrollment.

Inclusion Criteria:

• Age ≥18 years;
• Symptomatic COVID-19 disease within the last 14 days;
• Positive polymerase chain reaction (PCR) test for SARS-CoV-2 within the last 14 days;
• Need of hospitalization (duration ≥ 48 hours).

Exclusion Criteria:

• Severe comorbidity with life expectancy less than 3 months;
• Death during hospitalization;
• Absence of telephone contact;
• Absence of proxy for patients with communication difficulties;
• Refusal or withdrawal of agreement to participate;
• Previous enrollment in the study.