Probiotic in Treatment of Adult Patients With Drug-resistant Epilepsy

Investigation of Probiotic Effect on Seizure Frequency of Adult Patients With Drug-resistant Epilepsy; A Randomized Double-blind Parallel Placebo-controlled Clinical Trial

This study is a randomized, double-blind parallel group placebo-controlled clinical trial with the aim of investigating the effect of probiotic versus placebo on drug-resistant adult patients with epilepsy.

Inclusion Criteria:

Drug resistant epilepsy

Exclusion Criteria:

• Hypersensitivity to probiotic
• Acute pancreatitis
• Pregnancy
• Breastfeeding
• Being under treatment with corticosteroids
• Being under treatment with antibiotics during 2 months before enrollment
• Need for antibiotic therapy during the study
• Change in anti-seizure medication within the month before enrollment