| Primary | Percentage of Participants According to Number of Blood Tests at 1 to 4 Weeks From Palbociclib Treatment Initiation | Percentage of participants according to number of blood tests (0, 1, 2, 3, 4 and >=5) at 1 to 4 weeks after administration of palbociclib is reported in this outcome measure. | All eligible participants who were enrolled and whose data was included in the study. Here, "Overall Number of Participants Analyzed" signifies number of participants evaluable for this outcome measure. | Posted | | Number | | Percentage of participants | | Anytime between 1 to 4 weeks from palbociclib treatment initiation; available data observed retrospectively over approximately 22 months in this study | | | | ID | Title | Description |
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| OG000 | Participants With HR+/HER- Breast Cancer | Japanese participants diagnosed with hormone receptor positive/human epidermal growth factor receptor 2 negative (HR+/HER2-) breast cancer who had >=1 prescription record of endocrine therapy and initiated treatment with palbociclib following drug launch in Japan (15-Dec-2017) were included in the study. |
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| 0 | | | | 1 | | | | 2 | | |
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| Primary | Percentage of Participants According to Number of Blood Tests at 5 to 8 Weeks From Palbociclib Treatment Initiation | Percentage of participants according to number of blood tests (0, 1, 2, 3, 4 and >=5) at 5 to 8 weeks after administration of palbociclib is reported in this outcome measure. | All eligible participants who were enrolled and whose data was included in the study. Here, "Overall Number of Participants Analyzed" signifies number of participants evaluable for this outcome measure. | Posted | | Number | | Percentage of participants | | Anytime between 5 to 8 weeks from palbociclib treatment initiation; available data observed retrospectively over approximately 22 months in this study | | | | ID | Title | Description |
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| OG000 | Participants With HR+/HER- Breast Cancer | Japanese participants diagnosed with hormone receptor positive/human epidermal growth factor receptor 2 negative (HR+/HER2-) breast cancer who had >=1 prescription record of endocrine therapy and initiated treatment with palbociclib following drug launch in Japan (15-Dec-2017) were included in the study. |
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| Primary | Percentage of Participants According to Number of Blood Tests at 9 to 12 Weeks From Palbociclib Treatment Initiation | Percentage of participants according to number of blood tests (0, 1, 2, 3, 4 and >=5) at 9 to 12 weeks after administration of palbociclib is reported in this outcome measure. | All eligible participants who were enrolled and whose data was included in the study. Here, "Overall Number of Participants Analyzed" signifies number of participants evaluable for this outcome measure. | Posted | | Number | | Percentage of participants | | Anytime between 9 to 12 weeks from palbociclib treatment initiation; available data observed retrospectively over approximately 22 months in this study | | | | ID | Title | Description |
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| OG000 | Participants With HR+/HER- Breast Cancer | Japanese participants diagnosed with hormone receptor positive/human epidermal growth factor receptor 2 negative (HR+/HER2-) breast cancer who had >=1 prescription record of endocrine therapy and initiated treatment with palbociclib following drug launch in Japan (15-Dec-2017) were included in the study. |
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| Primary | Percentage of Participants According to Number of Blood Tests at 13 to 16 Weeks From Palbociclib Treatment Initiation | Percentage of participants according to number of blood tests (0, 1, 2, 3, 4 and >=5) at 13 to 16 weeks after administration of palbociclib is reported in this outcome measure. | All eligible participants who were enrolled and whose data was included in the study. Here, "Overall Number of Participants Analyzed" signifies number of participants evaluable for this outcome measure. | Posted | | Number | | Percentage of participants | | Anytime between 13 to 16 weeks from palbociclib treatment initiation; available data observed retrospectively over approximately 22 months in this study | | | | ID | Title | Description |
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| OG000 | Participants With HR+/HER- Breast Cancer | Japanese participants diagnosed with hormone receptor positive/human epidermal growth factor receptor 2 negative (HR+/HER2-) breast cancer who had >=1 prescription record of endocrine therapy and initiated treatment with palbociclib following drug launch in Japan (15-Dec-2017) were included in the study. |
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| Primary | Percentage of Participants According to Number of Blood Tests at 17 to 20 Weeks From Palbociclib Treatment Initiation | Percentage of participants according to number of blood tests (0, 1, 2, 3, 4 and >=5) at 17 to 20 weeks after administration of palbociclib is reported in this outcome measure. | All eligible participants who were enrolled and whose data was included in the study. Here, "Overall Number of Participants Analyzed" signifies number of participants evaluable for this outcome measure. | Posted | | Number | | Percentage of participants | | Anytime between 17 to 20 weeks from palbociclib treatment initiation; available data observed retrospectively over approximately 22 months in this study | | | | ID | Title | Description |
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| OG000 | Participants With HR+/HER- Breast Cancer | Japanese participants diagnosed with hormone receptor positive/human epidermal growth factor receptor 2 negative (HR+/HER2-) breast cancer who had >=1 prescription record of endocrine therapy and initiated treatment with palbociclib following drug launch in Japan (15-Dec-2017) were included in the study. |
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| Primary | Time to Treatment Failure of Palbociclib | Time to treatment failure of palbociclib was defined as time from the date of first palbociclib prescription to the date of lost to follow-up or to the date of the next line of therapy, defined as the end of palbociclib treatment. Time to treatment failure of palbociclib was censored at participant disenrollment or end of study period. | All eligible participants who were enrolled and whose data was included in the study. | Posted | | Median | 95% Confidence Interval | Months | | From start of palbociclib treatment until end of palbociclib treatment or censoring date (maximum up to 42.5 months); available data observed retrospectively over approximately 22 months in this study | | | | ID | Title | Description |
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| OG000 | Participants With HR+/HER- Breast Cancer | Japanese participants diagnosed with hormone receptor positive/human epidermal growth factor receptor 2 negative (HR+/HER2-) breast cancer who had >=1 prescription record of endocrine therapy and initiated treatment with palbociclib following drug launch in Japan (15-Dec-2017) were included in the study. |
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| Secondary | Mean Palbociclib Daily Dose | | All eligible participants who were enrolled and whose data was included in the study. | Posted | | Mean | Standard Deviation | Milligrams per day | | From start of palbociclib treatment until end of palbociclib treatment or end of study period (maximum up to 42.5 months); available data observed retrospectively over approximately 22 months in this study | | | | ID | Title | Description |
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| OG000 | Participants With HR+/HER- Breast Cancer | Japanese participants diagnosed with hormone receptor positive/human epidermal growth factor receptor 2 negative (HR+/HER2-) breast cancer who had >=1 prescription record of endocrine therapy and initiated treatment with palbociclib following drug launch in Japan (15-Dec-2017) were included in the study. |
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| Secondary | Number of Participants According to Regimen of First Subsequent Therapy After End of Palbociclib | Number of participants according to regimen of first subsequent therapy after end of palbociclib at first line and second line are reported in this outcome measure. The regimen was defined as any breast cancer treatment(s) received within 30 days of earlier treatment initiation. Only regimens used by >=3 participants in participants treated with palbociclib in the first or second line settings were reported. One participant may be included in more than one regimen. | All eligible participants who were enrolled and whose data was included in the study. Here, 'Overall Number of Participants Analyzed' signifies number of participants evaluable for this outcome measure and 'Number Analyzed' signifies number of participants evaluable for the specified rows. | Posted | | Count of Participants | | Participants | | From first subsequent therapy until end of study period (maximum up to 38.1 months); available data observed retrospectively over approximately 22 months in this study | | | | ID | Title | Description |
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| OG000 | Participants With HR+/HER- Breast Cancer | Japanese participants diagnosed with hormone receptor positive/human epidermal growth factor receptor 2 negative (HR+/HER2-) breast cancer who had >=1 prescription record of endocrine therapy and initiated treatment with palbociclib following drug launch in Japan (15-Dec-2017) were included in the study. |
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| Secondary | Time to Treatment Failure of Subsequent Therapy After End of Palbociclib | Time to treatment failure of subsequent therapy after palbociclib was defined as time from the date of first next line of therapy after end of palbociclib treatment to the date of lost to follow-up or to the date of the second next line of therapy. Time to treatment failure was censored at participant disenrollment or end of study period. | All eligible participants who were enrolled and whose data was included in the study. Here, 'Overall Number of Participants Analyzed' signifies number of participants evaluable for this outcome measure. | Posted | | Median | 95% Confidence Interval | Months | | From start of first subsequent therapy until date of lost to follow-up or date of next line of therapy or censoring date (maximum up to 38.1 months); available data observed retrospectively over approximately 22 months in this study | | | | ID | Title | Description |
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| OG000 | Participants With HR+/HER- Breast Cancer | Japanese participants diagnosed with hormone receptor positive/human epidermal growth factor receptor 2 negative (HR+/HER2-) breast cancer who had >=1 prescription record of endocrine therapy and initiated treatment with palbociclib following drug launch in Japan (15-Dec-2017) were included in the study. |
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| Other Pre-specified | Body Mass Index (BMI) at Palbociclib Initiation | BMI was calculated using the formula: BMI=(weight)/(height/100)^2. | All eligible participants who were enrolled and whose data was included in the study. Here, 'Overall Number of Participants Analyzed' signifies number of participants evaluable for this outcome measure. | Posted | | Mean | Standard Deviation | Kilogram per meter square | | At palbociclib initiation; available data observed retrospectively over approximately 22 months in this study | | | | ID | Title | Description |
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| OG000 | Participants With HR+/HER- Breast Cancer | Japanese participants diagnosed with hormone receptor positive/human epidermal growth factor receptor 2 negative (HR+/HER2-) breast cancer who had >=1 prescription record of endocrine therapy and initiated treatment with palbociclib following drug launch in Japan (15-Dec-2017) were included in the study. |
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| Other Pre-specified | Charlson Comorbidity Index at Palbociclib Initiation | Charlson Comorbidity Index predicts the ten-year mortality for a participant who may have a range of comorbid conditions. 17 comorbidities were assessed with associated weights from 1 to 6, based on the adjusted risk of mortality. The total score is derived by summing up the weights of comorbid conditions presented. The minimum score value is 0 and maximum is 37. A higher score means a greater mortality risk. | All eligible participants who were enrolled and whose data was included in the study. | Posted | | Mean | Standard Deviation | Units on a scale | | At palbociclib initiation; available data observed retrospectively over approximately 22 months in this study | | | | ID | Title | Description |
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| OG000 | Participants With HR+/HER- Breast Cancer | Japanese participants diagnosed with hormone receptor positive/human epidermal growth factor receptor 2 negative (HR+/HER2-) breast cancer who had >=1 prescription record of endocrine therapy and initiated treatment with palbociclib following drug launch in Japan (15-Dec-2017) were included in the study. |
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| Other Pre-specified | Number of Participants According to Index Year for Palbociclib Initiation | Index year was considered as the year corresponding to the start date of the first palbociclib line. Number of participants according to index year (2017, 2018, 2019, 2020, 2021) are reported in this outcome measure. | All eligible participants who were enrolled and whose data was included in the study. | Posted | | Count of Participants | | Participants | | Palbociclib initiation in 2017, 2018, 2019, 2020, 2021; available data observed retrospectively over approximately 22 months in this study | | | | ID | Title | Description |
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| OG000 | Participants With HR+/HER- Breast Cancer | Japanese participants diagnosed with hormone receptor positive/human epidermal growth factor receptor 2 negative (HR+/HER2-) breast cancer who had >=1 prescription record of endocrine therapy and initiated treatment with palbociclib following drug launch in Japan (15-Dec-2017) were included in the study. |
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| Other Pre-specified | Percentage of Participants According to Type of First Subsequent Breast Cancer Treatment After End of Palbociclib as First Line | One participant may be included in more than one breast cancer treatment. | All eligible participants who were enrolled and whose data was included in the study. Here, 'Overall Number of Participants Analyzed' signifies number of participants evaluable for this outcome measure. | Posted | | Number | | Percentage of participants | | From first subsequent therapy until end of study period (maximum up to 38.1 months); available data observed retrospectively over approximately 22 months in this study | | | | ID | Title | Description |
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| OG000 | Participants With HR+/HER- Breast Cancer | Japanese participants diagnosed with hormone receptor positive/human epidermal growth factor receptor 2 negative (HR+/HER2-) breast cancer who had >=1 prescription record of endocrine therapy and initiated treatment with palbociclib following drug launch in Japan (15-Dec-2017) were included in the study. |
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| Other Pre-specified | Number of Participants With Antibiotic Use During Palbociclib Treatment | | All eligible participants who were enrolled and whose data was included in the study. | Posted | | Count of Participants | | Participants | | From start of palbociclib treatment until end of palbociclib treatment or end of study period (maximum up to 42.5 months); available data observed retrospectively over approximately 22 months in this study | | | | ID | Title | Description |
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| OG000 | Participants With HR+/HER- Breast Cancer | Japanese participants diagnosed with hormone receptor positive/human epidermal growth factor receptor 2 negative (HR+/HER2-) breast cancer who had >=1 prescription record of endocrine therapy and initiated treatment with palbociclib following drug launch in Japan (15-Dec-2017) were included in the study. |
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| Other Pre-specified | Number of Participants With Granulocyte-Colony Stimulating Factor (G-CSF) Use During Palbociclib Treatment | | All eligible participants who were enrolled and whose data was included in the study. | Posted | | Count of Participants | | Participants | | From start of palbociclib treatment until end of palbociclib treatment or end of study period (maximum up to 42.5 months); available data observed retrospectively over approximately 22 months in this study | | | | ID | Title | Description |
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| OG000 | Participants With HR+/HER- Breast Cancer | Japanese participants diagnosed with hormone receptor positive/human epidermal growth factor receptor 2 negative (HR+/HER2-) breast cancer who had >=1 prescription record of endocrine therapy and initiated treatment with palbociclib following drug launch in Japan (15-Dec-2017) were included in the study. |
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| Other Pre-specified | Number of Participants According to Type of Endocrine Therapy Combined With Palbociclib | Number of participants according to the type of endocrine therapy (fulvestrant, letrozole, exemestane, anastrozole, tamoxifen, toremifen and other) combined with palbociclib at first line, second line and third line is reported in this outcome measure. "Other" included participants prescribed >=1 endocrine therapies and those prescribed medroxyprogesterone. | All eligible participants who were enrolled and whose data was included in the study. Here, 'Overall Number of Participants Analyzed' signifies number of participants evaluable for this outcome measure and 'Number Analyzed' signifies number of participants evaluable for the specified rows. | Posted | | Count of Participants | | Participants | | From start of palbociclib treatment until end of palbociclib treatment or end of study period (maximum up to 42.5 months); available data observed retrospectively over approximately 22 months in this study | | | | ID | Title | Description |
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| OG000 | Participants With HR+/HER- Breast Cancer | Japanese participants diagnosed with hormone receptor positive/human epidermal growth factor receptor 2 negative (HR+/HER2-) breast cancer who had >=1 prescription record of endocrine therapy and initiated treatment with palbociclib following drug launch in Japan (15-Dec-2017) were included in the study. |
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