Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The aim of the present study was to assess the effects of a combined therapy of aerobic exercise and transcranial photobiomodulation upon the cardinal motor sympomts of Parkinson´s disease of a group of Parkinson´s disease patients. It was hypothesized that aerobic exercise and transcranial photobiomodulation would yield significant benefits in the cardinal motor sympomts of the illness.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention aerobic (IAER) | Experimental | Patients assigned to the IAER participated in fourty-eigth aerobic exercise therapy sessions over the course of six months. |
|
| Intervention photobiomodulation (IPBM) | Experimental | Patients assigned to the IPBM participated in fourty-eigth transcraneal photobiomodulation (PBM) theraphy sessions, using a therapeutic laser console, over the course of six months. |
|
| Intervention aerobic and photobiomodulation (IAER+PBM9 | Experimental | Patients assigned to the IAER+PBM participated in the aerobic exercise therapy and the PBM one at the same time, during six months. |
|
| Control (CO) | No Intervention | Patients assigned to the control (CO) did not participated in any kind of therapy, they just followed their usual weekly routine during six months |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Aerobic training | Other | Cycling at the aerobic intensity |
|
| Measure | Description | Time Frame |
|---|---|---|
| MDS-UPDRS | The motor portion of the Movement Disorder Society-Unified Parkinson´s (MDS-UPDRS, the minimum and maximum values are 0 and 72, respectively and the higher score, the worse patient condition) | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| DASH | The disabilities of the arm, shoulder and hand (DASH, the minimun and maximum values are 0 and 190, respectively and the higher score, the worse patient condition) | 6 months |
| Static posturography |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Physical Education and Sport, University of León | León | Castille and León | 24071 | Spain |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41171380 | Derived | Santos L, Burtscher J, de Taboada L. Parkinson's disease, aerobic exercise and photobiomodulation: a randomised controlled trial. J Neural Transm (Vienna). 2025 Oct 31. doi: 10.1007/s00702-025-03050-7. Online ahead of print. |
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D028022 | Low-Level Light Therapy |
| ID | Term |
|---|---|
| D053685 | Laser Therapy |
| D013812 | Therapeutics |
| D010789 | Phototherapy |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Photobiomodulation | Other | Photons therapy |
|
The centre of pressure (CoP) parameters (these CoP parameters; Length, in mm, Area in mm2 and Speed, Xspeed and Yspeed in m/s will be combined to report the static posturography)
| 6 months |
| TMWT | 10 meters walking test (speed in seconds) | 6 months |
| TUG | Time up Go Test (speed in seconds) | 6 months |
| Grip strength | Grip strength in kg | 6 months |
| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |