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Disc degeneration is a natural part of growing older. Up to 60% of asymptomatic people have MRI findings that are positive. As a result, MRI only provides morphological information and may not be able to determine the clinical significance of the findings.
Many authors believe that patients who suffer from cervical radiculopathy as a result of degenerative disease and have multilevel pathology on imaging studies still have moderate surgical outcomes. This occurs due to a misdiagnosis or the need to perform surgery on multiple levels despite a single painful lesion.
Although the complication rate for 1- and 2-level ACDF is so low that it is considered one of the safest procedures in spine surgery. There is concern that increasing levels of fusion will lead to more complications, such as a higher incidence of persistent axial neck pain, dysphagia, and vertebral artery injury, as well as more postoperative pain and higher narcotic dosages.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group C | Active Comparator | selective anterior cervical discectomy and fusion (ACDF) |
|
| Group SNRB | Experimental | US-guided selective nerve root block (SNRB) then selective anterior cervical discectomy and fusion (ACDF) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| selective anterior cervical discectomy and fusion (ACDF) | Procedure | selective anterior cervical discectomy and fusion (ACDF) |
|
| Measure | Description | Time Frame |
|---|---|---|
| pain intensity | Visual analogue score (VAS): 0= no pain, 10= worst pain | 24 hours postoperative |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Assiut governorate | Asyut | 715715 | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30560028 | Background | Kreitz TM, Hollern DA, Padegimas EM, Schroeder GD, Kepler CK, Vaccaro AR, Hilibrand AS. Clinical Outcomes After Four-Level Anterior Cervical Discectomy and Fusion. Global Spine J. 2018 Dec;8(8):776-783. doi: 10.1177/2192568218770763. Epub 2018 Apr 24. | |
| 33036003 | Background | McClure JJ, Desai BD, Shabo LM, Buell TJ, Yen CP, Smith JS, Shaffrey CI, Shaffrey ME, Buchholz AL. A single-center retrospective analysis of 3- or 4-level anterior cervical discectomy and fusion: surgical outcomes in 66 patients. J Neurosurg Spine. 2020 Oct 9;34(1):45-51. doi: 10.3171/2020.6.SPINE20171. Print 2021 Jan 1. |
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| SNRB+ selective anterior cervical discectomy and fusion (ACDF) | Procedure | US-guided selective nerve root block (SNRB) + selective anterior cervical discectomy and fusion (ACDF) |
|
| 27054454 | Background | Ross DA, Ross MN. Diagnosis and Treatment of C4 Radiculopathy. Spine (Phila Pa 1976). 2016 Dec 1;41(23):1790-1794. doi: 10.1097/BRS.0000000000001620. |
| ID | Term |
|---|---|
| D050939 | Gene Fusion |
| ID | Term |
|---|---|
| D011995 | Recombination, Genetic |
| D055614 | Genetic Phenomena |
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