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| ID | Type | Description | Link |
|---|---|---|---|
| Ahmed Ali | Other Identifier | minia university faculty of medicine |
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One of this method's drawbacks is the healing of cauterized cartilage after processing. It was reported that the healing is so slow as no dosage form can reach this place in addition to the scares produced from healing is very irritable to the patient.
From this point, the investigators start searching for a solution to this problem and reach the repositioning of Vitamin D3 (calciferol) as an active ingredient for the rapidity and efficacy of burn healing.
The dosage form of choice that was reported before for intranasal application by the same team of investigators and gave good results. the intranasal films were proved for its convince, simplicity, efficacy, and compliance to patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| vitamin D film | Experimental | Prepared intranasal films containing vitamin D3 by the investigators and administered to the right nostril with the aid of an ENT surgeon |
|
| control group | Other | No devices will be added |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Vitamin D3 | Drug | intranasal film |
|
| Measure | Description | Time Frame |
|---|---|---|
| Healing of cauterized tissues after surgery procedures | The outcome will be measured by endoscopic scanning pre and after application of the drug in the dosage form (representing the percent of healing) by the ENT surgeon. | three week |
| Measure | Description | Time Frame |
|---|---|---|
| patients compliance from the new dosage form | The patient compliance will be measured by rating the pain and the development of symptoms before surgery using a questionnaire | three weeks |
| Assessment of grades of healing by ENT surgeon |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Minya university, faculty of medicin | Minya | Minya Governorate | 05673 | Egypt |
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| ID | Term |
|---|---|
| D015508 | Nasal Obstruction |
| ID | Term |
|---|---|
| D009668 | Nose Diseases |
| D012140 | Respiratory Tract Diseases |
| D000402 | Airway Obstruction |
| D012131 | Respiratory Insufficiency |
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| ID | Term |
|---|---|
| D002762 | Cholecalciferol |
| ID | Term |
|---|---|
| D002782 | Cholestenes |
| D002776 | Cholestanes |
| D013256 | Steroids |
| D000072473 | Fused-Ring Compounds |
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Evaluation of (1) bleeding (amount and frequencies), (2) crustation ( amount and nature), and (3) inflammation (size and the redness of the place of surgery)
| three weeks |
| D012120 |
| Respiration Disorders |
| D010038 | Otorhinolaryngologic Diseases |
| D011083 |
| Polycyclic Compounds |
| D013261 | Sterols |
| D014807 | Vitamin D |
| D012632 | Secosteroids |
| D008563 | Membrane Lipids |
| D008055 | Lipids |