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| ID | Type | Description | Link |
|---|---|---|---|
| R01EY031777 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Eye Institute (NEI) | NIH |
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The investigators are developing a new test of pedestrian hazard detection in virtual reality (VR) head-mounted display (HMD) headset, which shows virtual oncoming pedestrians in 3D while subjects are walking in real-world environment, for evaluation of visual field expansion to improve mobility in people with visual field loss.
The investigators will develop a new pedestrian hazard detection test and conduct a single arm interventional clinical trial to evaluate simulated low vision assistive devices in a sample of field loss subjects. Pedestrian detection performance with and without field expansion information will be tested and compared. The study will include 1 to 4 visits (each 2 to 4 hours) depending on the number of trials and experimental conditions (e.g., with and without simulated assistive devices) the subject is comfortable completing. The time between visits may vary depending on scheduling constraints and availability. During each visit, the subject will complete a series of simulated collision avoidance trials in VR requiring the detection and natural avoidance of a colliding pedestrian (alongside non-colliding pedestrians) while physically walking through an empty corridor. The study will be considered minimal-risk since there will be no physical obstacles that present actual collision risks.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Field expansion view | Experimental | Various configurations of field expansion views will be additionally displayed on HMD |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Field expansion view | Other | Overlaid small window on HMD to show the part of the scene in the blind field into portions of the participants' remaining, seeing, field of vision |
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| Measure | Description | Time Frame |
|---|---|---|
| Response time | During the pedestrian detection task, average response time to the colliding pedestrian with and without prisms | Through study completion, an average of four months |
| Measure | Description | Time Frame |
|---|---|---|
| Head movement range | During the pedestrian detection task, lateral and vertical head movement range to check the head scanning range | Through study completion, an average of four months |
| Walking speed |
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Inclusion criteria:
Exclusion criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Eli Peli, OD, MSc | Senior Scientist | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Schepens Eye Research Institute | Boston | Massachusetts | 02114 | United States |
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During the pedestrian detection task, the physical walking speed of the subject
| Through study completion, an average of four months |
| Pedestrian detection rate | Proportion of simulated pedestrians detected (in HMD walking) | Through study completion, an average of four months |
| Error rate | Proportion of false alarms and missed targets to total targets | Through study completion, an average of four months |
| ID | Term |
|---|---|
| D006423 | Hemianopsia |
| ID | Term |
|---|---|
| D014786 | Vision Disorders |
| D012678 | Sensation Disorders |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D001766 | Blindness |
| D005128 | Eye Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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