Biomarkers of Increased Risk of Developing Metabolic Adaptation to Weight Loss
Biomarkers of Increased Risk of Developing Metabolic Adaptation to Weight Loss
This study aims at identifying the neurohormonal biomarkers that characterize individuals at risk of greater metabolic adaptation to weight loss, a disproportionate decline in resting metabolic rate during and after weight loss.
Inclusion Criteria:
BMI > or = 30 any ethnicity
Exclusion Criteria:
weight > or = 400 lbs.
diabetes (type 2 or type 1)
hypertension
heart disease
kidney disease
liver disease
active cancer
post solid organ or bone marrow transplant
HIV/AIDS
pregnancy
breastfeeding
current smoker
current recreational drug use