Study of serum calcium and phosphorus level in chronic kidney disease patients and its relation to occurrence of acute coronary syndrome in them.

Prospective study to :

1. find the relation between electrolytes disturbance and renal diseases
2. the effect of electrolyte abnormalities on atherosclerosis
3. prevalence of acute coronary syndrome in patients with chronic kidney disease

Inclusion Criteria:

• 1-The CKD patients with or without dialysis who admitted to coronary care unit with chest pain consistent with ACS with any of following features :

  a- Electrocardiogram (ECG) changes:

• ST elevation.

• ST depression.

• T wave inversion.

• recent left bundle branch block.

  b- Troponin T elevation.

  2-The CKD patient with or without dialysis with no previous history of ACS.

Exclusion Criteria:

1. Patients who were diagnosed with primary hyperparathyroidism.

2. Acute Kidney injury (AKI) which is defined as any of the following:(KDIGO2012)

   • Increase in S.Cr by ≥ 0.3 mg/dl (≥ 26.5 μmol/l) within 48hours; or
   • Increase in S.Cr to ≥ 1.5 times baseline, which is known or presumed to have occurred within the prior 7 days;or
   • Urine volume <0.5 ml/kg/h for 6 hours

two groups :

1. CKD patients with and without dialysis who admitted to Sohag university hospital with acute coronary syndrome
2. CKD patients with and without dialysis who admitted to Sohag university hospital with no previous or current history of acute coronary syndrome