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This is a prospective, cohort, randomized clinical trial examining the effect of simple renal cysts on renal function.
This study is planned to include patients from S.I. Spasokukotskiy Citi Clinical Hospital with simple renal accidentally discovered cyst.
The aim of the study is to evaluate the impact of simple renal cysts on renal function and explore the correlation between cyst's size, parenchymal atrophy, and renal function.
After receiving the results, the analysis of the data obtained is carried out.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| kidneys with simple cysts | Experimental | Patients involve from Citi Clinical Hospital with simple renal accidentally discovered cyst. |
|
| contralateral kidneys without cyst | Active Comparator | Ð atients involve from Citi Clinical Hospital with simple renal accidentally discovered cyst. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| CT scan with contrast | Procedure | CT scan with contrast is necessary to determine the position of renal cysts, their location, and size (determine volume of atrophic parenchyma will be calculated). |
| Measure | Description | Time Frame |
|---|---|---|
| Renal function | Glomerular filtration rate (GFR, ml/min/1.73 m2) is a test used to check how well the kidneys are working. Specifically, it estimates how much blood passes through the glomeruli each minute. A GFR of 60 or higher is in the normal range. A GFR below 60 may mean kidney disease. A GFR of 15 or lower may mean kidney failure. The measurement of the glomerular filtration rate will be measured according to the results of the blood test and the results of nephroscintigraphy | 1 month |
| Measure | Description | Time Frame |
|---|---|---|
| Ratio of cyst size and volume of atrophic renal parenchyma | Computed tomography with contrast will be used to determine the position of renal cysts, their location, size and volume of atrophic parenchyma (cm2) are calculated | 1 month |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Vigen Malkhasyan | Contact | +7(909) 644-16-88 | vigenmalkhasyan@gmail.com | |
| Sergey Sukhikh | Contact | +7(985) 307-74-50 | docsukhikh@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Tukhtasin Mahmudov | Moscow state university of medicine and dentistry named after A.I. Evdokimov | Principal Investigator |
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| ID | Term |
|---|---|
| D003287 | Contrast Media |
| ID | Term |
|---|---|
| D064907 | Diagnostic Uses of Chemicals |
| D020228 | Pharmacologic Actions |
| D020164 | Chemical Actions and Uses |
| D020313 | Specialty Uses of Chemicals |
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We present a cohort study of patients with renal cysts (the first group - kidneys with cysts, the second group - kidneys without cysts in the studied patients). All patients will undergo contrast-enhanced CT of the urinary system (volume of atrophic parenchyma will be calculated), as well as nephroscintigraphy.
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| Nephroscintigraphy | Radiation | Nephroscintigraphy is necessary to determine the renal function |
|