Evaluating the Response of the Immune System of People with Long COVID (post SARS-CoV-2)

Immune Response to Post Acute Sequelae of SARSCoV2: a Correlation of Clinical Symptoms and Inflammatory Pathways

Many people who have had COVID 19 continue to experience symptoms long after they have recovered from the acute infection. This study will examine the clinical symptoms of people with "Long COVID" and measure various markers of inflammation in their blood.

Patients who attend the Long Covid Recovery Clinic at Huntington Hospital will be offered participation in the study. After giving written informed consent, their medical history along with a description of clinical symptoms given through an extensive questionnaire will be accessed. Venous blood will be collected as a baseline and then at follow up visits (as dictated by changes in clinical symptomatology) for evaluation of corollary immune parameters. Patients will be followed at a minimum of every 2 months for 2 years.

Inclusion Criteria:

• Enrolled in Huntington Hospital's Long Covid Recovery Clinic
• Documented previous infection with SARS-CoV2
• Symptoms suggestive of post-acute sequelae of SARS-CoV2 (including but not limited to chronic fatigue, brain fog, muscle and joint pain, cardiac and pulmonary issues, or other factors related to their acute COVID-19 event)
• Signed Informed Consent Form

Exclusion Criteria:

• No documented positive SARS-CoV2 serologies
• No post-acute sequelae of SARS-CoV2 symptomatology
• Incarcerated