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| Name | Class |
|---|---|
| MediService AG | UNKNOWN |
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This is a clinical study to improve the regularity of medication intake for high blood pressure. Adult women and men who are over 50 years old, who have received a prescription drug for high blood pressure from MediService, and who have to take at least 4 tablets per day (of which at least 1 dose of medication per day is for high blood pressure) can participate in this study.
The investigators intend to examine whether Collabree, a mobile phone application, is effective in supporting patients with hypertension to more successfully following their therapy plan in order to improve the regularity of medication intake.
The study includes a 90-day intervention phase and a 90-day follow-up. The study does not require any therapy adjustments and no visits to a study center are necessary. The participants conduct the study independently at home. Participants will also fill out questionnaires.
Participants are randomly assigned to one of 3 groups in a ratio of 1: 1: 1. Two of these groups will receive the Collabree mobile phone application.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention Group A | Experimental | Patients receive the Collabree mobile phone application with a specific set of functions. |
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| Intervention Group B | Experimental | Patients receive the Collabree mobile phone application with a specific set of functions. |
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| Control Group | No Intervention | Patients will not receive the Collabree application. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Collabree Mobile Phone Application Medication Adherence Booster | Behavioral | Patients take part in a 90-day program to promote medication adherence and a 90-day follow-up through the Collabree application. Patients will receive more information as to the exact functions and use of the mobile phone application when the application is installed on their mobile phone. |
| Measure | Description | Time Frame |
|---|---|---|
| Medication Adherence | Difference between intervention Group A and the control group in mean medication adherence at endpoint (i.e. the endpoint visit at 90 days) as measured by pill count. | 90 days |
| Measure | Description | Time Frame |
|---|---|---|
| Medication adherence (3 group comparison) | Mean change from baseline in medication adherence (monitored by pill count) at endpoint for the intervention Group A vs. intervention Group B relative to the control group. | 90 days |
| Self-reported medication adherence |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Anjali Raja Beharelle, PhD | Collabree AG | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Collabree AG | Zurich | Canton of Zurich | 8002 | Switzerland |
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| Collabree Mobile Phone Application Medication Adherence Booster (simplified version) | Behavioral | Patients take part in a 90-day program to promote medication adherence and a 90-day follow-up through the Collabree application. Patients will receive more information as to the exact functions and use of the mobile phone application when the application is installed on their mobile phone. |
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Mean change from baseline in in-app medication adherence (defined as the number of medications self-reported as "taken" during the intervention period of 90 days divided by the number of prescribed medications listed in the in-app medication plan in that same time period) at endpoint for the intervention Group A vs. intervention Group B relative to the control group. |
| 90 days |
| Self-assessed medication adherence | Mean change from baseline in the score on the Hill-Bone Scale (German version) questionnaire on medication adherence for the intervention Group A vs. intervention Group B relative to the control group at endpoint. The Hill-Bone Compliance to Blood Pressure Therapy Scale (German) scores can range from 14 to 56. A higher score means worse compliance. | 90 days |
| ID | Term |
|---|---|
| D006973 | Hypertension |
| D055118 | Medication Adherence |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D010349 | Patient Compliance |
| D010342 | Patient Acceptance of Health Care |
| D000074822 | Treatment Adherence and Compliance |
| D015438 | Health Behavior |
| D001519 | Behavior |
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