Esophageal atresia is a rare but severe malformation, and it requires early surgery. Coloesophagoplasty is surgical repair of the esophageal with an isoperistaltic transverse colon graft. In the postoperative period after coloesophagoplasty children require careful monitoring of fluid balance, because clinically significant fluid overload can lead to dysfunction of various organs and systems.

Esophageal atresia (EA) is a defect of the embryogenesis of the laryngotracheal tube. There are isolated forms of EA and combinations with a tracheoesophageal fistula (TPF). Esophageal plastic surgery with an isoperistaltic transplant from the transverse colon was performed in children with EA. After this surgical intervention children require observation in the intensive care unit (ICU). During this period, infusion therapy satisfies physiological needs and compensates for physiological and pathological losses. However, it is not always possible to compensate for the body's fluid needs and maintain a normovolemic state. Thus, fluid overload develops. It is based on a pathophysiological process when severe operational stress leads to the damage of glycocalyx in the vascular wall. As a result, albumin freely passes into the interstitium, and oncotic pressure rises in tissues. Fluid overload in the intra- and postoperative period can be a factor in an unfavorable outcome, leading to organ damage, as well as death.

Inclusion Criteria:

• Аge from 1 month to 3 years
• EA with / without
• Tracheoesophageal fistula (TPF)
• Сoloesophagoplasty.

Exclusion Criteria:

• Аesophageal burn,
• Oesophageal peptic stenosis,
• Congenital heart disease
• Cardiotonic support in the postoperative period
• Renal malformations
• Bacterial pneumonia in the postoperative period,
• Bronchopulmonary malformations.

40 children with EA with/without TPF, aged from 1 month to 3 years, who underwent coloesophagoplasty at the N.F. Filatov Children city Hospital, Moscow, Russia, from December 1, 2017 to December 31, 2020.