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This study will compare Hight Tibial Osteotomy with or without arthroscopically repair intra-articular knee lesions in patients with early stages of Osteoarthritis.The purpose of this study is evaluate if addition of arthroscopy to HTO provides better clinical, radiological and laboratory outcomes.
Intraarticular knee lesions are often in patients with early stages of osteoarthritis. The most frequent findings are degenerative meniscus/meniscal tears and cartilage degeneration. Degenerative meniscal lesions or meniscal tears are often incidental findings without any complains from patients. In the current literature there is no evidence for good clinical outcomes after arthroscopically treatment degenerative meniscus. Cartilage injuries are common in osteoarthritic knee and depending on grading of chondromalacia are usually treated by microfractures. By this time the choice of performed surgery depends on surgeons personal assessment. The investigators believe that concomitant intraarticular procedures added to HTO will provide better clinical outcomes.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| High Tibial Osteotomy and arthroscopy | Active Comparator | High Tibial Osteotomy with arthroscopically treatment of intraarticular lesions. |
|
| High Tibial Osteotomy | Sham Comparator | Descending High Tibial Osteotomy with arthroscopy without treatment of intraarticular lesions. |
|
| High Tibial Osteotomy, arthroscopy and microfractures | Active Comparator | High Tibial Osteotomy with arthroscopically treatment of intraarticular lesions and microfracture. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| HTO | Procedure | Hight Tibial Osteotomy |
|
| Measure | Description | Time Frame |
|---|---|---|
| KOOS | Knee Injury and Osteoarthritis Outcome Score | 12 months |
| KOOS | Knee Injury and Osteoarthritis Outcome Score | 24 months |
| IKDC | International Knee Documentation Committee - Subjective Knee Evaluation Form | 12 months |
| IKDC | International Knee Documentation Committee - Subjective Knee Evaluation Form | 24 months |
| VAS | Visual Analog Scale | 12 months |
| VAS | Visual Analog Scale | 24 months |
| Blood test | no inflammatory reaction - CRP, Il-6, CTx | 2 day |
| Blood test | no inflammatory reaction - CRP, Il-6, CTx | 6 weeks |
| Blood test | no inflammatory reaction - CRP, Il-6, CTx | 12 weeks, |
| Measure | Description | Time Frame |
|---|---|---|
| Kinematic MRI with [chondrogram] | Meniscus healing, cartilage quality | 2 day, |
| Kinematic MRI with [chondrogram] | Meniscus healing, cartilage quality |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Rafał Kamiński | Contact | +48227794031 | 469 | rkaminski@spskgruca.pl |
| Name | Affiliation | Role |
|---|---|---|
| Rafał Kamiński | PCME, Otwock, Poland | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Orthopaedics and Traumatology, Centre of Postgraduate Medical Education, Professor A. Gruca Teaching Hospital | Recruiting | Otwock | Masovian Voivodeship | 05-400 | Poland |
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| ID | Term |
|---|---|
| D020370 | Osteoarthritis, Knee |
| D010003 | Osteoarthritis |
| D015775 | Fractures, Stress |
| ID | Term |
|---|---|
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D012216 | Rheumatic Diseases |
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| Arthroscopy treatment | Procedure | Arthroscopy treatment |
|
| Micro fractures | Procedure | Micro fractures |
|
| 24 months |
| X-ray - Baldini projection | Patellofemoral joint measurements | 2 day |
| X-ray - Baldini projection | Patellofemoral joint measurements | 24 months |
|
| D050723 |
| Fractures, Bone |
| D014947 | Wounds and Injuries |