After acute infection, patients with coronavirus disease 2019 (COVID-19) often suffer from persisting symptoms for more than 3 months (post COVID-19). Sleep disorders (31%) have already been assessed by questionnaires and interviews in post-COVID-19, but have not yet been proven by polysomnography (PSG), the gold standard for sleep testing. This study aimed to measure sleep characteristics in post-COVID-19 patients.

Hypothesis: We hypothesize that post-COVID-19 patients have a significantly higher apnea-hypopnea index (AHI) during sleep compared to healthy controls.

15 post-COVID-19 patients and 15 healthy controls will perform a baseline assessment on day 1 including a 1-minute sit-to-stand test (STST), post-COVID functional scale (PCFS), Ordinal Scale for Clinical Improvement (OSCI), history of COVID-19, social anamnesis, Pittsburgh Sleep Questionnaire and subjective limitations of sleep.

On day 4, after an initialization phase for WHOOP strap (a digital fitness and health coach), all patients performed a single night sleep assessment in a sleep lab via Polysomnography and WHOOP.

Inclusion Criteria:

Post-COVID-19 Group:

• Patients after SARS-CoV-2 infection with signs of Post-COVID-19
• ≥18 years
• written informed consent

Healthy controls:

• No history of SARS-CoV-2 infection
• ≥18 years
• written informed consent

Exclusion Criteria:

Post-COVID-19 Group:

• Diagnosis of a breathing-related sleep disorder before SARS-CoV-2 infection
• BMI >25kg/m2

Healthy controls:

• Diagnosis of a breathing-related sleep disorder
• BMI >25kg/m2

30 patients will be included in this study. Patients with Post-COVID-19 (n=15) are characterized by Symptoms usually starting 3 months following the onset of COVID-19 that last for at least 2 months and cannot be explained by an alternative diagnosis than SARS-CoV-2 infection.

Healthy controls are characterized by having no history of SARS-CoV-2 infection.